Actiq
Actiq is a solid formulation of fentanyl citrate on a stick, designed to dissolve slowly in the mouth to facilitate oral transmucosal absorption. Fentanyl is a potent Schedule II opioid agonist. Actiq is subject to a Risk Evaluation and Mitigation Strategy (REMS) program due to risk of misuse, abuse, addiction, and overdose.
Dosage by Body Weight
Individually titrate to an effective dose that provides adequate analgesia and minimizes adverse reactions. The initial dose is 200 mcg. No more than two doses of Actiq should be used to treat any single breakthrough pain episode. Patients must be opioid-tolerant.
- Body Weight
- Below 5 kg
- Dose
- Contraindicated
- Frequency
- Do not use
- Tracking Notes
- Actiq is contraindicated in pediatric patients and opioid-non-tolerant individuals. Accidental ingestion of even a single dose can be fatal to a child.
- Body Weight
- 5-7 kg
- Dose
- Contraindicated
- Frequency
- Do not use
- Tracking Notes
- Not indicated or safe for pediatric patients. High risk of fatal respiratory depression.
- Body Weight
- 8-10 kg
- Dose
- Contraindicated
- Frequency
- Do not use
- Tracking Notes
- Not indicated or safe for pediatric patients. Keep out of reach of children at all times.
- Body Weight
- 11-15 kg
- Dose
- Contraindicated
- Frequency
- Do not use
- Tracking Notes
- Not indicated or safe for pediatric patients.
- Body Weight
- 16-20 kg
- Dose
- Contraindicated
- Frequency
- Do not use
- Tracking Notes
- Not indicated or safe for pediatric patients.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Contraindicated | Do not use | Actiq is contraindicated in pediatric patients and opioid-non-tolerant individuals. Accidental ingestion of even a single dose can be fatal to a child. |
| 5-7 kg | Contraindicated | Do not use | Not indicated or safe for pediatric patients. High risk of fatal respiratory depression. |
| 8-10 kg | Contraindicated | Do not use | Not indicated or safe for pediatric patients. Keep out of reach of children at all times. |
| 11-15 kg | Contraindicated | Do not use | Not indicated or safe for pediatric patients. |
| 16-20 kg | Contraindicated | Do not use | Not indicated or safe for pediatric patients. |
Formulation
Purpose
Management of breakthrough cancer pain in patients 16 years of age and older who are already receiving and who are tolerant to around-the-clock opioid therapy for their underlying persistent cancer pain.
Generic Name
Fentanyl citrateScheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.