Sitagliptin
Sitagliptin is an oral dipeptidyl peptidase-4 (DPP-4) inhibitor class of antidiabetic drug. It works by increasing the levels of natural substances called incretins, which help to control blood sugar by increasing insulin release, especially after a meal, and decreasing the amount of sugar made by the liver.
Dosage by Body Weight
The standard dose for adults is 100 mg taken orally once daily, with or without food. Dose adjustments (50 mg or 25 mg once daily) are required for patients with moderate to severe renal impairment or end-stage renal disease. Always consult a healthcare provider before initiating or adjusting treatment.
- Body Weight
- Below 5 kg
- Dose
- Not recommended
- Frequency
- N/A
- Tracking Notes
- Safety and efficacy have not been established in pediatric patients.
- Body Weight
- 5-7 kg
- Dose
- Not recommended
- Frequency
- N/A
- Tracking Notes
- Safety and efficacy have not been established in pediatric patients.
- Body Weight
- 8-10 kg
- Dose
- Not recommended
- Frequency
- N/A
- Tracking Notes
- Safety and efficacy have not been established in pediatric patients.
- Body Weight
- 11-15 kg
- Dose
- Not recommended
- Frequency
- N/A
- Tracking Notes
- Safety and efficacy have not been established in pediatric patients.
- Body Weight
- 16-20 kg
- Dose
- Not recommended
- Frequency
- N/A
- Tracking Notes
- Safety and efficacy have not been established in pediatric patients.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Not recommended | N/A | Safety and efficacy have not been established in pediatric patients. |
| 5-7 kg | Not recommended | N/A | Safety and efficacy have not been established in pediatric patients. |
| 8-10 kg | Not recommended | N/A | Safety and efficacy have not been established in pediatric patients. |
| 11-15 kg | Not recommended | N/A | Safety and efficacy have not been established in pediatric patients. |
| 16-20 kg | Not recommended | N/A | Safety and efficacy have not been established in pediatric patients. |
Formulation
Purpose
Improves glycemic control in adults with type 2 diabetes mellitus as an adjunct to diet and exercise.
Generic Name
SitagliptinBranded Drug Names
Sitagliptin is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:
Scheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.