Rifabutin
A rifamycin antibiotic. It is used instead of rifampicin in HIV patients because it has fewer drug-drug interactions with antiretroviral medications.
Dosage by Body Weight
Pediatric dose: 5 mg/kg once daily. Monitor for uveitis (eye inflammation) and low white blood cell counts.
- Body Weight
- 15-30 kg
- Dose
- 75 mg to 150 mg
- Frequency
- Once daily
- Tracking Notes
- Take with food if stomach upset occurs.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| 15-30 kg | 75 mg to 150 mg | Once daily | Take with food if stomach upset occurs. |
Formulation
Purpose
Prevention and treatment of Mycobacterium avium complex (MAC) in children with HIV.
Generic Name
RifabutinBranded Drug Names
Rifabutin is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:
Scheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.
Alternatives
Safety Advice
Alcohol
CAUTIONRifabutin: Alcohol may worsen infection-related dehydration, dizziness, or stomach upset. Avoid or limit alcohol during antibiotic treatment.
Pregnancy
SAFE IF PRESCRIBEDRifabutin: Use during pregnancy only when prescribed for a bacterial infection; the prescriber will choose the safest suitable antibiotic.
Breast Feeding
SAFE IF PRESCRIBEDRifabutin: Many antibiotics are compatible with breastfeeding when prescribed, but monitor the infant for diarrhea, rash, or thrush.
Driving
SAFERifabutin: Usually does not affect driving, but dizziness, weakness, or illness symptoms can occur. Avoid driving if affected.
Liver
CAUTIONRifabutin: Use caution in liver disease or if jaundice, dark urine, or severe fatigue occurs during treatment.
Kidney
CAUTIONRifabutin: Some antibiotics require dose adjustment or monitoring in kidney disease. Use exactly as prescribed.