Ondansetron

Ondansetron blocks the actions of chemicals in the body that can trigger nausea and vomiting.

Dosage by Body Weight

Often used off-label for acute gastroenteritis in children to prevent dehydration. Dosing is typically 0.15 mg/kg.

Weight-based dosage tracking table for Ondansetron, including body weight, dose, frequency, and tracking notes.
Body Weight	Dose	Frequency	Tracking Notes
8-15 kg	2 mg	Every 8 hours as needed	ODT (melt-in-mouth) is useful if the child is vomiting.
15-30 kg	4 mg	Every 8 hours as needed	Do not exceed prescribed frequency.

TabletOrally Disintegrating Tablet (ODT)SyrupInjection

Used to prevent nausea and vomiting, especially that caused by chemotherapy, radiation, or surgery.

Ondansetron is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:

Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.

CAUTION

Alcohol may worsen nausea, dizziness, or dehydration while taking ondansetron. Avoid or limit alcohol until vomiting has resolved.

SAFE IF PRESCRIBED

Ondansetron may be prescribed in pregnancy when benefits outweigh risks, particularly for severe nausea. Use only under medical advice.

SAFE IF PRESCRIBED

Ondansetron is generally considered compatible with breastfeeding when prescribed. Consult your healthcare provider if repeated doses are needed.

CAUTION

Ondansetron may cause dizziness, fatigue, or blurred vision in some people. Avoid driving if you feel affected.

CAUTION

Ondansetron may require dose limits or monitoring in moderate to severe liver impairment. Consult your healthcare provider.

SAFE IF PRESCRIBED

Ondansetron generally does not require kidney dose adjustment, but use as prescribed if you have serious kidney disease.