Granisetron
A selective 5-HT3 receptor antagonist. It works by blocking serotonin, a natural substance that causes vomiting.
Dosage by Body Weight
Pediatric dose: 10 mcg/kg to 20 mcg/kg per dose. Usually given 1 hour before chemotherapy starts.
- Body Weight
- 15-30 kg
- Dose
- 0.5 mg to 1 mg
- Frequency
- Once or twice daily
- Tracking Notes
- May cause headaches or constipation.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| 15-30 kg | 0.5 mg to 1 mg | Once or twice daily | May cause headaches or constipation. |
Formulation
Purpose
Prevention of nausea and vomiting caused by chemotherapy or surgery.
Generic Name
Granisetron HydrochlorideBranded Drug Names
Granisetron is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:
Scheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.
Alternatives
Safety Advice
Alcohol
CAUTIONGranisetron: Alcohol can worsen stomach irritation, dehydration, dizziness, or bowel symptoms. Avoid or limit alcohol.
Pregnancy
SAFE IF PRESCRIBEDGranisetron: Use during pregnancy only when prescribed or recommended by a healthcare provider for the specific condition.
Breast Feeding
SAFE IF PRESCRIBEDGranisetron: Use while breastfeeding only as directed; monitor the infant for diarrhea, drowsiness, or feeding changes when relevant.
Driving
SAFEGranisetron: Usually does not affect driving, but dizziness, cramps, or weakness can occur. Avoid driving if affected.
Liver
CAUTIONGranisetron: Use caution in significant liver disease or when the medicine is used for liver-related complications.
Kidney
CAUTIONGranisetron: Kidney disease or dehydration can increase side-effect risk for some gastrointestinal medicines. Use with medical guidance.