Captopril
One of the first ACE inhibitors. It has a short half-life, which allows for rapid dose adjustment in a clinical setting.
Dosage by Body Weight
In infants, starting doses are very low (0.1 mg/kg) and titrated. Requires frequent blood pressure monitoring.
- Body Weight
- 5-10 kg
- Dose
- 0.5 mg to 5 mg
- Frequency
- Two to three times daily
- Tracking Notes
- Administer 1 hour before meals.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| 5-10 kg | 0.5 mg to 5 mg | Two to three times daily | Administer 1 hour before meals. |
Formulation
Purpose
ACE inhibitor used for hypertension and heart failure in infants and children.
Generic Name
CaptoprilBranded Drug Names
Captopril is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:
Scheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.
Alternatives
Safety Advice
Alcohol
CAUTIONCaptopril: Alcohol can increase dizziness, low blood pressure, dehydration, or heart rhythm symptoms. Avoid or limit alcohol.
Pregnancy
CAUTIONCaptopril: Use in pregnancy only when prescribed; some heart or blood pressure medicines are not suitable during pregnancy.
Breast Feeding
SAFE IF PRESCRIBEDCaptopril: Use while breastfeeding only with healthcare provider guidance, as infant monitoring may be needed.
Driving
CAUTIONCaptopril: May cause dizziness, faintness, tiredness, or blurred vision, especially when starting or changing dose. Avoid driving if affected.
Liver
CAUTIONCaptopril: Liver disease may alter medicine handling and increase side effects. Use with medical supervision.
Kidney
CAUTIONCaptopril: Kidney function and electrolytes may need monitoring, especially with diuretics, ACE inhibitors, ARBs, or digoxin.