Vorier
Vorier contains Voriconazole, a broad-spectrum triazole antifungal agent. It works by inhibiting the synthesis of ergosterol, an essential component of fungal cell membranes, thereby stopping the growth of the fungi. It is a potent prescription medication requiring careful monitoring of liver function and drug interactions.
Dosage by Body Weight
Must be taken under strict medical supervision. Tablets should be taken on an empty stomach, at least one hour before or one hour after a meal. Dosages are highly individualized based on the patient's age, weight, and the severity of the fungal infection.
- Body Weight
- Below 5 kg
- Dose
- Not routine
- Frequency
- Use only if prescribed
- Tracking Notes
- Safety and efficacy are not established in infants under 2 years of age or weighing less than 5 kg.
- Body Weight
- 5-7 kg
- Dose
- Requires specialist calculation
- Frequency
- Every 12 hours
- Tracking Notes
- Pediatric dosing for ages 2 to 12 is generally calculated on a mg/kg basis. Strict specialist supervision is mandatory.
- Body Weight
- 8-10 kg
- Dose
- 9 mg/kg (Oral Suspension)
- Frequency
- Every 12 hours
- Tracking Notes
- Standard pediatric oral dose is 9 mg/kg twice daily for children aged 2 to <12 years.
- Body Weight
- 11-15 kg
- Dose
- 9 mg/kg (Oral Suspension)
- Frequency
- Every 12 hours
- Tracking Notes
- Do not exceed adult maximum maintenance doses. Liver function tests must be monitored.
- Body Weight
- 16-20 kg
- Dose
- 9 mg/kg (Oral Suspension) or 100 mg (Tablet)
- Frequency
- Every 12 hours
- Tracking Notes
- If the child can swallow tablets safely, a tablet formulation may be considered under medical guidance.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Not routine | Use only if prescribed | Safety and efficacy are not established in infants under 2 years of age or weighing less than 5 kg. |
| 5-7 kg | Requires specialist calculation | Every 12 hours | Pediatric dosing for ages 2 to 12 is generally calculated on a mg/kg basis. Strict specialist supervision is mandatory. |
| 8-10 kg | 9 mg/kg (Oral Suspension) | Every 12 hours | Standard pediatric oral dose is 9 mg/kg twice daily for children aged 2 to <12 years. |
| 11-15 kg | 9 mg/kg (Oral Suspension) | Every 12 hours | Do not exceed adult maximum maintenance doses. Liver function tests must be monitored. |
| 16-20 kg | 9 mg/kg (Oral Suspension) or 100 mg (Tablet) | Every 12 hours | If the child can swallow tablets safely, a tablet formulation may be considered under medical guidance. |
Formulation
Purpose
Used to treat serious, invasive fungal infections including invasive aspergillosis, candidemia, esophageal candidiasis, and other deep tissue fungal infections.
Generic Name
VoriconazoleScheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.