Vancomycin (Systemic)
A glycopeptide antibiotic. Systemic use (IV) is reserved for severe infections like endocarditis or bone infections. It requires drug level monitoring (Trough levels) to avoid kidney toxicity.
Dosage by Body Weight
Pediatric dose: 15 mg/kg every 6 to 8 hours. Infusion must be slow (at least 60 mins) to prevent 'Red Man Syndrome'.
- Body Weight
- 10-20 kg
- Dose
- 150 mg to 300 mg
- Frequency
- Every 6 to 8 hours
- Tracking Notes
- Blood trough levels are typically checked before the 4th dose.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| 10-20 kg | 150 mg to 300 mg | Every 6 to 8 hours | Blood trough levels are typically checked before the 4th dose. |
Formulation
Purpose
Treatment of serious infections caused by MRSA and other resistant Gram-positive bacteria.
Generic Name
Vancomycin HydrochlorideBranded Drug Names
Vancomycin (Systemic) is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:
Scheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.
Alternatives
Safety Advice
Alcohol
CAUTIONVancomycin (Systemic): Alcohol may worsen infection-related dehydration, dizziness, or stomach upset. Avoid or limit alcohol during antibiotic treatment.
Pregnancy
SAFE IF PRESCRIBEDVancomycin (Systemic): Use during pregnancy only when prescribed for a bacterial infection; the prescriber will choose the safest suitable antibiotic.
Breast Feeding
SAFE IF PRESCRIBEDVancomycin (Systemic): Many antibiotics are compatible with breastfeeding when prescribed, but monitor the infant for diarrhea, rash, or thrush.
Driving
SAFEVancomycin (Systemic): Usually does not affect driving, but dizziness, weakness, or illness symptoms can occur. Avoid driving if affected.
Liver
CAUTIONVancomycin (Systemic): Use caution in liver disease or if jaundice, dark urine, or severe fatigue occurs during treatment.
Kidney
CAUTIONVancomycin (Systemic): Some antibiotics require dose adjustment or monitoring in kidney disease. Use exactly as prescribed.