Valproic Acid
Works by increasing the levels of GABA (an inhibitory neurotransmitter) in the brain. Requires careful blood monitoring.
Dosage by Body Weight
Initial pediatric dose is 10-15 mg/kg/day, titrated up. Requires specialist neurologist supervision.
- Body Weight
- 10-20 kg
- Dose
- 150 mg to 300 mg total daily
- Frequency
- Divided into 2 doses
- Tracking Notes
- Monitor for side effects like hair loss, weight gain, or liver issues.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| 10-20 kg | 150 mg to 300 mg total daily | Divided into 2 doses | Monitor for side effects like hair loss, weight gain, or liver issues. |
Formulation
Purpose
Antiepileptic drug used for various types of seizures and sometimes for migraine prophylaxis.
Generic Name
Sodium ValproateBranded Drug Names
Valproic Acid is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:
Scheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.
Alternatives
Safety Advice
Alcohol
UNSAFEValproic Acid: Alcohol can significantly increase drowsiness, dizziness, breathing problems, or seizure risk. Avoid alcohol unless a specialist says otherwise.
Pregnancy
CAUTIONValproic Acid: Use in pregnancy only under specialist advice because seizure control and fetal risks must be carefully balanced.
Breast Feeding
SAFE IF PRESCRIBEDValproic Acid: May pass into breast milk and can cause infant drowsiness or feeding issues. Use only with healthcare provider guidance.
Driving
CAUTIONValproic Acid: Can cause drowsiness, slowed reaction time, dizziness, or blurred vision. Avoid driving until you know how it affects you.
Liver
CAUTIONValproic Acid: Some anti-seizure medicines can affect liver function and may require blood tests or dose adjustments.
Kidney
CAUTIONValproic Acid: Some anti-seizure medicines require dose adjustment in kidney impairment. Use under medical supervision.