Valganciclovir
A prodrug of ganciclovir. It is highly effective against CMV, which can be life-threatening in immunocompromised children or infants with congenital CMV.
Dosage by Body Weight
Pediatric dosing is complex, often calculated using the Mosteller Body Surface Area formula and creatinine clearance. For neonates with congenital CMV: 16 mg/kg twice daily.
- Body Weight
- 3-6 kg (Neonate)
- Dose
- 48 mg to 96 mg
- Frequency
- Twice daily
- Tracking Notes
- Must be taken with food. Handle with gloves (cytotoxic).
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| 3-6 kg (Neonate) | 48 mg to 96 mg | Twice daily | Must be taken with food. Handle with gloves (cytotoxic). |
Formulation
Purpose
Treatment of Cytomegalovirus (CMV) retinitis and prevention of CMV disease in transplant recipients.
Generic Name
Valganciclovir HydrochlorideBranded Drug Names
Valganciclovir is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:
Scheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.
Alternatives
Safety Advice
Alcohol
CAUTIONValganciclovir: Alcohol may worsen dizziness, nausea, dehydration, or liver strain during antiviral treatment. Avoid or limit alcohol.
Pregnancy
SAFE IF PRESCRIBEDValganciclovir: Use during pregnancy only when prescribed; treatment may be important for maternal infection control or prevention of transmission.
Breast Feeding
SAFE IF PRESCRIBEDValganciclovir: Breastfeeding advice depends on the infection and treatment regimen. Use only with healthcare provider guidance.
Driving
CAUTIONValganciclovir: May cause dizziness, fatigue, sleep disturbance, or headache. Avoid driving if alertness is affected.
Liver
CAUTIONValganciclovir: Some antivirals can affect liver function or require monitoring in hepatitis, HIV, or severe illness.
Kidney
CAUTIONValganciclovir: Several antivirals are cleared by the kidneys and may need dose adjustment or hydration. Consult your healthcare provider.