Trimethoprim / Sulfamethoxazole
A synergistic combination of two antibiotics that blocks two consecutive steps in the bacterial synthesis of nucleic acids and proteins.
Dosage by Body Weight
Dosed based on the Trimethoprim (TMP) component (typically 8 mg/kg/day divided into two doses). Avoid in infants under 2 months.
- Body Weight
- 5-10 kg
- Dose
- 40 mg TMP / 200 mg SMZ
- Frequency
- Twice daily
- Tracking Notes
- Equivalent to 5 ml of standard pediatric suspension.
- Body Weight
- 11-20 kg
- Dose
- 80 mg TMP / 400 mg SMZ
- Frequency
- Twice daily
- Tracking Notes
- Ensure the child drinks plenty of fluids to prevent crystals in urine.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| 5-10 kg | 40 mg TMP / 200 mg SMZ | Twice daily | Equivalent to 5 ml of standard pediatric suspension. |
| 11-20 kg | 80 mg TMP / 400 mg SMZ | Twice daily | Ensure the child drinks plenty of fluids to prevent crystals in urine. |
Formulation
SuspensionTablet
Purpose
Combination antibiotic (Co-trimoxazole) used for UTIs, respiratory infections, and ear infections.
Generic Name
Co-trimoxazole
Branded Drug Names
Trimethoprim / Sulfamethoxazole is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:
- Bactrim
- Septra
- Sepmax
Scheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.