Trimethoprim / Sulfamethoxazole

A synergistic combination of two antibiotics that blocks two consecutive steps in the bacterial synthesis of nucleic acids and proteins.

Dosage by Body Weight

Dosed based on the Trimethoprim (TMP) component (typically 8 mg/kg/day divided into two doses). Avoid in infants under 2 months.

Body Weight
5-10 kg
Dose
40 mg TMP / 200 mg SMZ
Frequency
Twice daily
Tracking Notes
Equivalent to 5 ml of standard pediatric suspension.
Body Weight
11-20 kg
Dose
80 mg TMP / 400 mg SMZ
Frequency
Twice daily
Tracking Notes
Ensure the child drinks plenty of fluids to prevent crystals in urine.

Weight-based dosage tracking table for Trimethoprim / Sulfamethoxazole, including body weight, dose, frequency, and tracking notes.
Body Weight	Dose	Frequency	Tracking Notes
5-10 kg	40 mg TMP / 200 mg SMZ	Twice daily	Equivalent to 5 ml of standard pediatric suspension.
11-20 kg	80 mg TMP / 400 mg SMZ	Twice daily	Ensure the child drinks plenty of fluids to prevent crystals in urine.

Formulation

SuspensionTablet

Purpose

Combination antibiotic (Co-trimoxazole) used for UTIs, respiratory infections, and ear infections.

Generic Name

Co-trimoxazole

Branded Drug Names

Trimethoprim / Sulfamethoxazole is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:

Scheduled Drug

Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.

Alternatives

Amoxicillin Nitrofurantoin

Safety Advice

Alcohol

CAUTION

Trimethoprim / Sulfamethoxazole: Alcohol may increase dizziness, stomach upset, dehydration, or other side effects. Avoid or limit alcohol and follow medical advice.

Pregnancy

SAFE IF PRESCRIBED

Trimethoprim / Sulfamethoxazole: Use during pregnancy only if prescribed after a healthcare provider weighs the benefits and risks.

Breast Feeding

SAFE IF PRESCRIBED

Trimethoprim / Sulfamethoxazole: Use while breastfeeding only with healthcare provider guidance, especially for repeated or long-term treatment.

Driving

CAUTION

Trimethoprim / Sulfamethoxazole: This medicine may cause dizziness, drowsiness, weakness, or blurred vision in some people. Avoid driving if affected.

Liver

CAUTION

Trimethoprim / Sulfamethoxazole: Use with caution in liver disease and consult your healthcare provider if you have abnormal liver tests or jaundice.

Kidney

CAUTION

Trimethoprim / Sulfamethoxazole: Use with caution in kidney disease because dose adjustment or monitoring may be needed for some patients.