Tirosint
Tirosint is a brand-name synthetic thyroid hormone (T4) used to replace thyroxine that the thyroid gland cannot produce enough of on its own. It is uniquely formulated as a gelatin soft capsule containing liquid levothyroxine, which contains no gluten, dyes, alcohol, lactose, or sugar. This formulation is designed to improve absorption, particularly in patients with gastrointestinal issues or food/chemical sensitivities.
Dosage by Body Weight
Dosages must be individualized based on clinical response and laboratory assessments (TSH and free T4 levels). It should be taken once daily in the morning on an empty stomach, at least 30 to 60 minutes before breakfast, with a full glass of water. Dosage adjustments should be supervised closely by a healthcare professional.
- Body Weight
- Below 5 kg
- Dose
- 25 - 50 mcg
- Frequency
- Once daily
- Tracking Notes
- Based on a typical pediatric dose of 10-15 mcg/kg/day. For infants, Tirosint-SOL (liquid) is preferred as the capsules should not be cut or crushed.
- Body Weight
- 5-7 kg
- Dose
- 40 - 70 mcg
- Frequency
- Once daily
- Tracking Notes
- Based on pediatric guideline of 8-10 mcg/kg/day. Monitor TSH and T4 levels closely to adjust dosage.
- Body Weight
- 8-10 kg
- Dose
- 50 - 80 mcg
- Frequency
- Once daily
- Tracking Notes
- Based on pediatric guideline of 6-8 mcg/kg/day. Administer on an empty stomach.
- Body Weight
- 11-15 kg
- Dose
- 55 - 90 mcg
- Frequency
- Once daily
- Tracking Notes
- Based on pediatric guideline of 5-6 mcg/kg/day. Highly dependent on individual metabolic demands.
- Body Weight
- 16-20 kg
- Dose
- 65 - 100 mcg
- Frequency
- Once daily
- Tracking Notes
- Based on pediatric guideline of 4-5 mcg/kg/day. Regular blood tests required to optimize dosing.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | 25 - 50 mcg | Once daily | Based on a typical pediatric dose of 10-15 mcg/kg/day. For infants, Tirosint-SOL (liquid) is preferred as the capsules should not be cut or crushed. |
| 5-7 kg | 40 - 70 mcg | Once daily | Based on pediatric guideline of 8-10 mcg/kg/day. Monitor TSH and T4 levels closely to adjust dosage. |
| 8-10 kg | 50 - 80 mcg | Once daily | Based on pediatric guideline of 6-8 mcg/kg/day. Administer on an empty stomach. |
| 11-15 kg | 55 - 90 mcg | Once daily | Based on pediatric guideline of 5-6 mcg/kg/day. Highly dependent on individual metabolic demands. |
| 16-20 kg | 65 - 100 mcg | Once daily | Based on pediatric guideline of 4-5 mcg/kg/day. Regular blood tests required to optimize dosing. |
Formulation
Purpose
Used to treat hypothyroidism (underactive thyroid) and to suppress thyroid-stimulating hormone (TSH) secretion in patients with thyroid cancer.
Generic Name
Levothyroxine sodiumScheduled Drug
No. This medicine is generally not treated as a scheduled/prescription-only drug in common consumer references, but local rules may vary.