Tenofovir Disoproxil Fumarate

A nucleotide reverse transcriptase inhibitor (NtRTI). It is highly effective but requires monitoring of bone density and kidney function in growing children.

Dosage by Body Weight

Pediatric dose: 8 mg/kg once daily (max 300 mg). Generally recommended for children 2 years and older weighing at least 10 kg.

  1. Body Weight
    10-14 kg
    Dose
    80 mg to 100 mg
    Frequency
    Once daily
    Tracking Notes
    Oral powder can be mixed with soft foods.
  2. Body Weight
    28-35 kg
    Dose
    200 mg to 250 mg
    Frequency
    Once daily
    Tracking Notes
    Take with a meal to increase absorption.

Formulation

TabletOral Powder

Purpose

Treatment of HIV-1 and chronic Hepatitis B in children and adolescents.

Generic Name

Tenofovir DF (TDF)

Branded Drug Names

Tenofovir Disoproxil Fumarate is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:

Scheduled Drug

Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.

Alternatives

Safety Advice

Alcohol

CAUTION

Tenofovir Disoproxil Fumarate: Alcohol may worsen dizziness, nausea, dehydration, or liver strain during antiviral treatment. Avoid or limit alcohol.

Pregnancy

SAFE IF PRESCRIBED

Tenofovir Disoproxil Fumarate: Use during pregnancy only when prescribed; treatment may be important for maternal infection control or prevention of transmission.

Breast Feeding

SAFE IF PRESCRIBED

Tenofovir Disoproxil Fumarate: Breastfeeding advice depends on the infection and treatment regimen. Use only with healthcare provider guidance.

Driving

CAUTION

Tenofovir Disoproxil Fumarate: May cause dizziness, fatigue, sleep disturbance, or headache. Avoid driving if alertness is affected.

Liver

CAUTION

Tenofovir Disoproxil Fumarate: Some antivirals can affect liver function or require monitoring in hepatitis, HIV, or severe illness.

Kidney

CAUTION

Tenofovir Disoproxil Fumarate: Several antivirals are cleared by the kidneys and may need dose adjustment or hydration. Consult your healthcare provider.

Disclaimer: This information is for educational purposes only. WHO references and weight bands are simplified for tracking and must not replace medical advice. Always consult with a healthcare professional before starting or changing any medication.