Tenofovir Disoproxil Fumarate
A nucleotide reverse transcriptase inhibitor (NtRTI). It is highly effective but requires monitoring of bone density and kidney function in growing children.
Dosage by Body Weight
Pediatric dose: 8 mg/kg once daily (max 300 mg). Generally recommended for children 2 years and older weighing at least 10 kg.
- Body Weight
- 10-14 kg
- Dose
- 80 mg to 100 mg
- Frequency
- Once daily
- Tracking Notes
- Oral powder can be mixed with soft foods.
- Body Weight
- 28-35 kg
- Dose
- 200 mg to 250 mg
- Frequency
- Once daily
- Tracking Notes
- Take with a meal to increase absorption.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| 10-14 kg | 80 mg to 100 mg | Once daily | Oral powder can be mixed with soft foods. |
| 28-35 kg | 200 mg to 250 mg | Once daily | Take with a meal to increase absorption. |
Formulation
Purpose
Treatment of HIV-1 and chronic Hepatitis B in children and adolescents.
Generic Name
Tenofovir DF (TDF)Branded Drug Names
Tenofovir Disoproxil Fumarate is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:
Scheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.
Alternatives
Safety Advice
Alcohol
CAUTIONTenofovir Disoproxil Fumarate: Alcohol may worsen dizziness, nausea, dehydration, or liver strain during antiviral treatment. Avoid or limit alcohol.
Pregnancy
SAFE IF PRESCRIBEDTenofovir Disoproxil Fumarate: Use during pregnancy only when prescribed; treatment may be important for maternal infection control or prevention of transmission.
Breast Feeding
SAFE IF PRESCRIBEDTenofovir Disoproxil Fumarate: Breastfeeding advice depends on the infection and treatment regimen. Use only with healthcare provider guidance.
Driving
CAUTIONTenofovir Disoproxil Fumarate: May cause dizziness, fatigue, sleep disturbance, or headache. Avoid driving if alertness is affected.
Liver
CAUTIONTenofovir Disoproxil Fumarate: Some antivirals can affect liver function or require monitoring in hepatitis, HIV, or severe illness.
Kidney
CAUTIONTenofovir Disoproxil Fumarate: Several antivirals are cleared by the kidneys and may need dose adjustment or hydration. Consult your healthcare provider.