Tenof
Tenof contains Tenofovir Disoproxil Fumarate, a nucleotide reverse transcriptase inhibitor (NRTI). It works by blocking the activity of reverse transcriptase (in HIV) and viral polymerase (in Hepatitis B), preventing the virus from multiplying and lowering the viral load in the body.
Dosage by Body Weight
The standard adult dose is one 300 mg tablet once daily. It should be taken at the same time each day, with or without food. For children, dosage is strictly determined by a specialist based on weight and age.
- Body Weight
- Below 5 kg
- Dose
- Not recommended
- Frequency
- N/A
- Tracking Notes
- Safety and effectiveness have not been established in patients weighing less than 10 kg.
- Body Weight
- 5-7 kg
- Dose
- Not recommended
- Frequency
- N/A
- Tracking Notes
- Safety and effectiveness have not been established in patients weighing less than 10 kg.
- Body Weight
- 8-10 kg
- Dose
- Not recommended
- Frequency
- N/A
- Tracking Notes
- Standard 300 mg tablets are not suitable. Only pediatric powder formulations may be considered by a specialist.
- Body Weight
- 11-15 kg
- Dose
- Not recommended for 300 mg tablet
- Frequency
- N/A
- Tracking Notes
- Requires reduced pediatric strengths (e.g., 150 mg or 200 mg tablets) strictly as prescribed by a specialist.
- Body Weight
- 16-20 kg
- Dose
- 150 mg once daily (using pediatric low-dose tablets)
- Frequency
- Once daily
- Tracking Notes
- Do not use standard adult 300 mg Tenof tablets. Must be prescribed and monitored by a specialist.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Not recommended | N/A | Safety and effectiveness have not been established in patients weighing less than 10 kg. |
| 5-7 kg | Not recommended | N/A | Safety and effectiveness have not been established in patients weighing less than 10 kg. |
| 8-10 kg | Not recommended | N/A | Standard 300 mg tablets are not suitable. Only pediatric powder formulations may be considered by a specialist. |
| 11-15 kg | Not recommended for 300 mg tablet | N/A | Requires reduced pediatric strengths (e.g., 150 mg or 200 mg tablets) strictly as prescribed by a specialist. |
| 16-20 kg | 150 mg once daily (using pediatric low-dose tablets) | Once daily | Do not use standard adult 300 mg Tenof tablets. Must be prescribed and monitored by a specialist. |
Formulation
Tablet
Purpose
Treatment of HIV-1 infection (in combination with other antiretroviral agents) and chronic Hepatitis B virus (HBV) infection.
Generic Name
Tenofovir disoproxil fumarateScheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.