Sublimaze
Sublimaze is a highly potent, rapid-acting synthetic opioid analgesic used primarily in surgical and perioperative settings.
Dosage by Body Weight
Must be administered only by healthcare professionals trained in airway management and intravenous anesthesia. Dosage is individualized and titrated based on body weight, age, physical status, and surgical requirements.
- Body Weight
- Below 5 kg
- Dose
- 0.5 to 1 mcg/kg IV
- Frequency
- Single dose or titrated slowly
- Tracking Notes
- Extreme caution required due to risk of respiratory depression; monitor continuously.
- Body Weight
- 5-7 kg
- Dose
- 1 to 2 mcg/kg IV
- Frequency
- As clinically indicated
- Tracking Notes
- Administer slowly over 1 to 2 minutes to minimize muscle rigidity.
- Body Weight
- 8-10 kg
- Dose
- 1 to 2 mcg/kg IV
- Frequency
- As clinically indicated
- Tracking Notes
- Ensure resuscitation equipment and opioid antagonists (naloxone) are immediately available.
- Body Weight
- 11-15 kg
- Dose
- 1 to 2 mcg/kg IV
- Frequency
- As clinically indicated
- Tracking Notes
- Dose must be reduced when used in combination with other anesthetic agents or sedatives.
- Body Weight
- 16-20 kg
- Dose
- 1 to 2 mcg/kg IV
- Frequency
- As clinically indicated
- Tracking Notes
- Monitor oxygen saturation, heart rate, and blood pressure continuously.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | 0.5 to 1 mcg/kg IV | Single dose or titrated slowly | Extreme caution required due to risk of respiratory depression; monitor continuously. |
| 5-7 kg | 1 to 2 mcg/kg IV | As clinically indicated | Administer slowly over 1 to 2 minutes to minimize muscle rigidity. |
| 8-10 kg | 1 to 2 mcg/kg IV | As clinically indicated | Ensure resuscitation equipment and opioid antagonists (naloxone) are immediately available. |
| 11-15 kg | 1 to 2 mcg/kg IV | As clinically indicated | Dose must be reduced when used in combination with other anesthetic agents or sedatives. |
| 16-20 kg | 1 to 2 mcg/kg IV | As clinically indicated | Monitor oxygen saturation, heart rate, and blood pressure continuously. |
Formulation
Injection
Purpose
Anesthetic premedication, adjunct to general or regional anesthesia, and postoperative pain management.
Generic Name
Fentanyl CitrateScheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.