Spironolactone

Antagonizes aldosterone receptors in the kidney, promoting salt/water excretion while retaining potassium.

Dosage by Body Weight

Pediatric dose: 1-3 mg/kg/day. Avoid salt substitutes containing potassium.

  1. Body Weight
    5-10 kg
    Dose
    6.25 mg to 12.5 mg
    Frequency
    Once daily or divided
    Tracking Notes
    Monitor for high potassium (hyperkalemia).

Formulation

TabletSuspension

Purpose

Potassium-sparing diuretic used for heart failure, edema, and hyperaldosteronism.

Generic Name

Spironolactone

Branded Drug Names

Spironolactone is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:

Scheduled Drug

Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.

Alternatives

EplerenoneAmiloride

Safety Advice

Alcohol

CAUTION

Spironolactone: Alcohol can increase dizziness, low blood pressure, dehydration, or heart rhythm symptoms. Avoid or limit alcohol.

Pregnancy

CAUTION

Spironolactone: Use in pregnancy only when prescribed; some heart or blood pressure medicines are not suitable during pregnancy.

Breast Feeding

SAFE IF PRESCRIBED

Spironolactone: Use while breastfeeding only with healthcare provider guidance, as infant monitoring may be needed.

Driving

CAUTION

Spironolactone: May cause dizziness, faintness, tiredness, or blurred vision, especially when starting or changing dose. Avoid driving if affected.

Liver

CAUTION

Spironolactone: Liver disease may alter medicine handling and increase side effects. Use with medical supervision.

Kidney

CAUTION

Spironolactone: Kidney function and electrolytes may need monitoring, especially with diuretics, ACE inhibitors, ARBs, or digoxin.

Disclaimer: This information is for educational purposes only. WHO references and weight bands are simplified for tracking and must not replace medical advice. Always consult with a healthcare professional before starting or changing any medication.