Single Blind Food Challenge
A single-blind food challenge is a clinical diagnostic procedure where a patient ingests increasing amounts of a suspected food allergen under close medical supervision to determine if an allergic reaction occurs. In a single-blind setup, the patient does not know whether they are receiving the active allergen or a placebo (which helps eliminate psychological or subjective bias), while the medical supervisor knows what is being administered to manage clinical safety.
Dosage by Body Weight
Dosing is patient-specific, allergen-specific, and protocol-driven rather than body-weight dependent. Typically, escalating doses of the food allergen (starting from micrograms or milligrams of food protein up to a standard serving portion) are administered at set intervals (usually every 15-30 minutes) under direct medical supervision in a facility equipped to treat anaphylaxis.
- Body Weight
- Below 5 kg
- Dose
- Strictly clinical protocol-based
- Frequency
- Single diagnostic procedure
- Tracking Notes
- Rarely performed in this weight class. Must be conducted under the direct supervision of a pediatric allergist in a specialized facility.
- Body Weight
- 5-7 kg
- Dose
- Strictly clinical protocol-based
- Frequency
- Single diagnostic procedure
- Tracking Notes
- Doses start with minute amounts of food protein and are titrated upward according to standardized pediatric allergy protocols.
- Body Weight
- 8-10 kg
- Dose
- Strictly clinical protocol-based
- Frequency
- Single diagnostic procedure
- Tracking Notes
- Testing is stopped immediately at the first objective sign of an allergic reaction. Epinephrine must be drawn and ready.
- Body Weight
- 11-15 kg
- Dose
- Strictly clinical protocol-based
- Frequency
- Single diagnostic procedure
- Tracking Notes
- Dose escalation steps are determined by the specific allergen being tested. A post-challenge observation period of 2-4 hours is required.
- Body Weight
- 16-20 kg
- Dose
- Strictly clinical protocol-based
- Frequency
- Single diagnostic procedure
- Tracking Notes
- Administered incrementally until a full age-appropriate serving portion is tolerated or a reaction occurs.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Strictly clinical protocol-based | Single diagnostic procedure | Rarely performed in this weight class. Must be conducted under the direct supervision of a pediatric allergist in a specialized facility. |
| 5-7 kg | Strictly clinical protocol-based | Single diagnostic procedure | Doses start with minute amounts of food protein and are titrated upward according to standardized pediatric allergy protocols. |
| 8-10 kg | Strictly clinical protocol-based | Single diagnostic procedure | Testing is stopped immediately at the first objective sign of an allergic reaction. Epinephrine must be drawn and ready. |
| 11-15 kg | Strictly clinical protocol-based | Single diagnostic procedure | Dose escalation steps are determined by the specific allergen being tested. A post-challenge observation period of 2-4 hours is required. |
| 16-20 kg | Strictly clinical protocol-based | Single diagnostic procedure | Administered incrementally until a full age-appropriate serving portion is tolerated or a reaction occurs. |
Formulation
Purpose
Used as a diagnostic tool to identify or rule out specific food allergies, hypersensitivities, or adverse food reactions under controlled medical supervision.
Generic Name
Oral Food Challenge (Single Blind)Scheduled Drug
No. This medicine is generally not treated as a scheduled/prescription-only drug in common consumer references, but local rules may vary.