Rebetol
Rebetol (ribavirin) is an antiviral nucleoside analogue. It works by stopping the virus that causes hepatitis C from spreading inside the body. Rebetol must not be used alone as it is ineffective for treating chronic hepatitis C without companion therapy.
Dosage by Body Weight
Dosage is strictly calculated based on patient body weight, renal function, and the specific combination antiviral regimen. Typically administered twice daily (morning and evening) with food. It is highly teratogenic and contraindicated in pregnant women and male partners of pregnant women.
- Body Weight
- Below 5 kg
- Dose
- Not recommended
- Frequency
- N/A
- Tracking Notes
- Safety and efficacy have not been established in infants or patients in this weight category.
- Body Weight
- 5-7 kg
- Dose
- Not recommended
- Frequency
- N/A
- Tracking Notes
- Hepatitis C treatment is not routinely indicated for children in this weight range.
- Body Weight
- 8-10 kg
- Dose
- Not routinely recommended
- Frequency
- N/A
- Tracking Notes
- Pediatric dosing is typically reserved for children aged 3 years and older who usually exceed this weight. Consult a specialist.
- Body Weight
- 11-15 kg
- Dose
- 15 mg/kg/day (approx. 180 mg to 225 mg daily)
- Frequency
- Two divided doses daily (morning and evening with food)
- Tracking Notes
- Must be administered using oral solution. Use only under strict supervision of a pediatric hepatologist.
- Body Weight
- 16-20 kg
- Dose
- 15 mg/kg/day (approx. 240 mg to 300 mg daily)
- Frequency
- Two divided doses daily (morning and evening with food)
- Tracking Notes
- Requires close monitoring of hemoglobin levels and hepatic function. Oral solution is typically required for precise dosing.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Not recommended | N/A | Safety and efficacy have not been established in infants or patients in this weight category. |
| 5-7 kg | Not recommended | N/A | Hepatitis C treatment is not routinely indicated for children in this weight range. |
| 8-10 kg | Not routinely recommended | N/A | Pediatric dosing is typically reserved for children aged 3 years and older who usually exceed this weight. Consult a specialist. |
| 11-15 kg | 15 mg/kg/day (approx. 180 mg to 225 mg daily) | Two divided doses daily (morning and evening with food) | Must be administered using oral solution. Use only under strict supervision of a pediatric hepatologist. |
| 16-20 kg | 15 mg/kg/day (approx. 240 mg to 300 mg daily) | Two divided doses daily (morning and evening with food) | Requires close monitoring of hemoglobin levels and hepatic function. Oral solution is typically required for precise dosing. |
Formulation
Purpose
Used in combination with other antiviral medications, such as peginterferon alfa-2b or direct-acting antivirals, for the treatment of chronic hepatitis C virus (HCV) infection.
Generic Name
RibavirinScheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.