Pyridostigmine

An acetylcholinesterase inhibitor that improves muscle strength by preventing the breakdown of acetylcholine at the neuromuscular junction.

Dosage by Body Weight

Initial dose: 1 mg/kg every 4-6 hours. Titrated carefully by a pediatric neurologist.

  1. Body Weight
    10-20 kg
    Dose
    10 mg to 20 mg
    Frequency
    Every 4 to 6 hours
    Tracking Notes
    Monitor for excessive drooling or abdominal cramps.

Formulation

SyrupTablet

Purpose

Treatment of Myasthenia Gravis in children.

Generic Name

Pyridostigmine Bromide

Branded Drug Names

Pyridostigmine is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:

Scheduled Drug

Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.

Alternatives

Safety Advice

Alcohol

CAUTION

Pyridostigmine: Alcohol may increase dizziness, stomach upset, dehydration, or other side effects. Avoid or limit alcohol and follow medical advice.

Pregnancy

SAFE IF PRESCRIBED

Pyridostigmine: Use during pregnancy only if prescribed after a healthcare provider weighs the benefits and risks.

Breast Feeding

SAFE IF PRESCRIBED

Pyridostigmine: Use while breastfeeding only with healthcare provider guidance, especially for repeated or long-term treatment.

Driving

CAUTION

Pyridostigmine: This medicine may cause dizziness, drowsiness, weakness, or blurred vision in some people. Avoid driving if affected.

Liver

CAUTION

Pyridostigmine: Use with caution in liver disease and consult your healthcare provider if you have abnormal liver tests or jaundice.

Kidney

CAUTION

Pyridostigmine: Use with caution in kidney disease because dose adjustment or monitoring may be needed for some patients.

Disclaimer: This information is for educational purposes only. WHO references and weight bands are simplified for tracking and must not replace medical advice. Always consult with a healthcare professional before starting or changing any medication.