Prudoxin
Prudoxin is a topical cream containing 5% doxepin hydrochloride. It is a tricyclic antidepressant that, when applied topically, acts as a potent antihistamine (blocking both H1 and H2 receptors) to relieve severe itching associated with certain skin conditions like eczema.
Dosage by Body Weight
Apply a thin film to the affected areas four times daily, with at least a 3- to 4-hour interval between applications. Do not use for more than 8 days.
- Body Weight
- Below 5 kg
- Dose
- Not recommended
- Frequency
- N/A
- Tracking Notes
- Safety and efficacy in pediatric patients have not been established.
- Body Weight
- 5-7 kg
- Dose
- Not recommended
- Frequency
- N/A
- Tracking Notes
- Safety and efficacy in pediatric patients have not been established.
- Body Weight
- 8-10 kg
- Dose
- Not recommended
- Frequency
- N/A
- Tracking Notes
- Safety and efficacy in pediatric patients have not been established.
- Body Weight
- 11-15 kg
- Dose
- Not recommended
- Frequency
- N/A
- Tracking Notes
- Safety and efficacy in pediatric patients have not been established.
- Body Weight
- 16-20 kg
- Dose
- Not recommended
- Frequency
- N/A
- Tracking Notes
- Safety and efficacy in pediatric patients have not been established.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Not recommended | N/A | Safety and efficacy in pediatric patients have not been established. |
| 5-7 kg | Not recommended | N/A | Safety and efficacy in pediatric patients have not been established. |
| 8-10 kg | Not recommended | N/A | Safety and efficacy in pediatric patients have not been established. |
| 11-15 kg | Not recommended | N/A | Safety and efficacy in pediatric patients have not been established. |
| 16-20 kg | Not recommended | N/A | Safety and efficacy in pediatric patients have not been established. |
Formulation
Cream
Purpose
Short-term management of moderate pruritus (itching) in adult patients with atopic dermatitis or lichen simplex chronicus.
Generic Name
Doxepin hydrochlorideScheduled Drug
No. This medicine is generally not treated as a scheduled/prescription-only drug in common consumer references, but local rules may vary.