Protopic
Protopic is a prescription topical calcineurin inhibitor containing tacrolimus. It is designed to reduce skin inflammation and relieve itching associated with eczema by modulating the local immune response in the skin. It does not contain steroids and is available in 0.03% and 0.1% strengths.
Dosage by Body Weight
Apply a thin layer of Protopic ointment to the affected skin areas twice daily. Rub in gently and completely. Children aged 2 to 15 years should only use the 0.03% ointment. Adults may use either the 0.03% or 0.1% strength. Avoid occlusive dressings and limit sun exposure during use.
- Body Weight
- Below 5 kg
- Dose
- Contraindicated / Not recommended
- Frequency
- N/A
- Tracking Notes
- Safety and efficacy of Protopic have not been established in children under 2 years of age. Topical medication is not dosed by body weight.
- Body Weight
- 5-7 kg
- Dose
- Contraindicated / Not recommended
- Frequency
- N/A
- Tracking Notes
- Safety and efficacy of Protopic have not been established in children under 2 years of age. Topical medication is not dosed by body weight.
- Body Weight
- 8-10 kg
- Dose
- Not routine / Consult physician
- Frequency
- N/A
- Tracking Notes
- Usually corresponds to infants under 2 years of age for whom the drug is not approved. Topical medication is not dosed by body weight.
- Body Weight
- 11-15 kg
- Dose
- Apply thin layer (0.03% strength only)
- Frequency
- Twice daily
- Tracking Notes
- Only for children 2 years of age and older. Use the lower 0.03% strength. Apply only to affected areas. Topical medication is not dosed by body weight.
- Body Weight
- 16-20 kg
- Dose
- Apply thin layer (0.03% strength only)
- Frequency
- Twice daily
- Tracking Notes
- Only for children 2 years of age and older. Use the lower 0.03% strength. Apply only to affected areas. Topical medication is not dosed by body weight.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Contraindicated / Not recommended | N/A | Safety and efficacy of Protopic have not been established in children under 2 years of age. Topical medication is not dosed by body weight. |
| 5-7 kg | Contraindicated / Not recommended | N/A | Safety and efficacy of Protopic have not been established in children under 2 years of age. Topical medication is not dosed by body weight. |
| 8-10 kg | Not routine / Consult physician | N/A | Usually corresponds to infants under 2 years of age for whom the drug is not approved. Topical medication is not dosed by body weight. |
| 11-15 kg | Apply thin layer (0.03% strength only) | Twice daily | Only for children 2 years of age and older. Use the lower 0.03% strength. Apply only to affected areas. Topical medication is not dosed by body weight. |
| 16-20 kg | Apply thin layer (0.03% strength only) | Twice daily | Only for children 2 years of age and older. Use the lower 0.03% strength. Apply only to affected areas. Topical medication is not dosed by body weight. |
Formulation
Purpose
Treatment of moderate to severe atopic dermatitis (eczema) in patients who do not have a treatment response to or are intolerant of alternative, conventional therapies.
Generic Name
Tacrolimus topicalScheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.