Premarin (Conjugated Estrogens)
Premarin is a mixture of conjugated estrogens obtained from natural sources (specifically, the urine of pregnant mares). Estrogens are female sex hormones essential for the development and maintenance of the female reproductive system and secondary sex characteristics. Premarin helps replace estrogen when the body's natural levels drop during and after menopause.
Dosage by Body Weight
Dosage must be individualized based on the specific indication and patient response. It is typically administered cyclically (e.g., 21 days on, 7 days off) or continuously. Patients should be treated with the lowest effective dose for the shortest duration necessary to achieve treatment goals.
- Body Weight
- Below 5 kg
- Dose
- Not indicated
- Frequency
- Not applicable
- Tracking Notes
- Premarin is not indicated for pediatric use or infants in this weight range.
- Body Weight
- 5-7 kg
- Dose
- Not indicated
- Frequency
- Not applicable
- Tracking Notes
- Estrogen therapy is not recommended for children in this weight category.
- Body Weight
- 8-10 kg
- Dose
- Not indicated
- Frequency
- Not applicable
- Tracking Notes
- Estrogen therapy is not recommended for children in this weight category.
- Body Weight
- 11-15 kg
- Dose
- Not indicated
- Frequency
- Not applicable
- Tracking Notes
- Estrogen therapy is not indicated for pediatric use in this weight category unless specifically prescribed by a specialist for rare endocrine conditions.
- Body Weight
- 16-20 kg
- Dose
- Not indicated
- Frequency
- Not applicable
- Tracking Notes
- Premarin dosing is not determined by body weight and is highly restricted in pediatric populations.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Not indicated | Not applicable | Premarin is not indicated for pediatric use or infants in this weight range. |
| 5-7 kg | Not indicated | Not applicable | Estrogen therapy is not recommended for children in this weight category. |
| 8-10 kg | Not indicated | Not applicable | Estrogen therapy is not recommended for children in this weight category. |
| 11-15 kg | Not indicated | Not applicable | Estrogen therapy is not indicated for pediatric use in this weight category unless specifically prescribed by a specialist for rare endocrine conditions. |
| 16-20 kg | Not indicated | Not applicable | Premarin dosing is not determined by body weight and is highly restricted in pediatric populations. |
Formulation
Purpose
Hormone replacement therapy (HRT) used to treat moderate to severe vasomotor symptoms (hot flashes) and vulvar/vaginal atrophy associated with menopause. It is also used to prevent postmenopausal osteoporosis and treat hypoestrogenism caused by hypogonadism, castration, or primary ovarian failure.
Generic Name
Conjugated EstrogensScheduled Drug
No. This medicine is generally not treated as a scheduled/prescription-only drug in common consumer references, but local rules may vary.