Primaquine
Targets the 'hypnozoite' stage of the malaria parasite that hides in the liver. **Must test for G6PD deficiency before use** to avoid hemolytic anemia.
Dosage by Body Weight
Standard pediatric dose: 0.25–0.5 mg/kg daily for 14 days.
- Body Weight
- 10-15 kg
- Dose
- 3.75 mg to 7.5 mg
- Frequency
- Once daily for 14 days
- Tracking Notes
- Tablets may need to be crushed and mixed with sweet food.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| 10-15 kg | 3.75 mg to 7.5 mg | Once daily for 14 days | Tablets may need to be crushed and mixed with sweet food. |
Formulation
Purpose
Radical cure of P. vivax and P. ovale malaria to prevent relapse.
Generic Name
Primaquine PhosphateBranded Drug Names
Primaquine is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:
Scheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.
Alternatives
Safety Advice
Alcohol
CAUTIONPrimaquine: Alcohol may worsen dehydration, stomach upset, or interfere with nutritional recovery. Avoid or limit alcohol.
Pregnancy
SAFE IF PRESCRIBEDPrimaquine: Generally safe in pregnancy when used at recommended doses or as prescribed. Avoid excessive supplementation.
Breast Feeding
SAFEPrimaquine: Generally compatible with breastfeeding when used at recommended doses. Ask a healthcare provider before high-dose use.
Driving
SAFEPrimaquine: Usually does not affect driving. Avoid driving only if you feel unwell, dizzy, or weak from the underlying condition.
Liver
SAFE IF PRESCRIBEDPrimaquine: Usually safe at recommended doses, but high-dose or fat-soluble vitamin use should be medically supervised in liver disease.
Kidney
CAUTIONPrimaquine: Kidney disease may require avoiding or adjusting minerals and electrolytes such as potassium, magnesium, calcium, or phosphate.