Plasma-Lyte
Plasma-Lyte is a sterile, nonpyrogenic, isotonic intravenous solution designed to closely mimic the electrolyte profile and pH of human blood plasma. It contains sodium, potassium, magnesium, chloride, acetate, and gluconate. It helps restore fluid volume and physiological acid-base balance without causing hyperchloremic metabolic acidosis.
Dosage by Body Weight
Dosage must be individualized and titrated by a healthcare provider based on the patient's age, body weight, clinical condition, fluid balance, and laboratory determinations (electrolyte levels and acid-base status).
- Body Weight
- Below 5 kg
- Dose
- Calculated individually (approx. 100 mL/kg/24h for maintenance)
- Frequency
- Continuous intravenous infusion
- Tracking Notes
- Strict monitoring of electrolytes, fluid balance, and renal function is mandatory in neonates and infants.
- Body Weight
- 5-7 kg
- Dose
- Calculated individually (approx. 100 mL/kg/24h for maintenance)
- Frequency
- Continuous intravenous infusion
- Tracking Notes
- Rate must be adjusted based on clinical assessment, hydration status, and urine output.
- Body Weight
- 8-10 kg
- Dose
- Calculated individually (approx. 100 mL/kg/24h for maintenance)
- Frequency
- Continuous intravenous infusion
- Tracking Notes
- Ensure cardiorespiratory stability; monitor for signs of fluid overload.
- Body Weight
- 11-15 kg
- Dose
- 1000 mL + 50 mL for each kg over 10 kg per 24 hours
- Frequency
- Continuous intravenous infusion
- Tracking Notes
- Corresponds to approximately 40 to 52 mL/hour maintenance rate.
- Body Weight
- 16-20 kg
- Dose
- 1000 mL + 50 mL for each kg over 10 kg per 24 hours
- Frequency
- Continuous intravenous infusion
- Tracking Notes
- Corresponds to approximately 52 to 62 mL/hour maintenance rate. Adjust based on specific metabolic needs.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Calculated individually (approx. 100 mL/kg/24h for maintenance) | Continuous intravenous infusion | Strict monitoring of electrolytes, fluid balance, and renal function is mandatory in neonates and infants. |
| 5-7 kg | Calculated individually (approx. 100 mL/kg/24h for maintenance) | Continuous intravenous infusion | Rate must be adjusted based on clinical assessment, hydration status, and urine output. |
| 8-10 kg | Calculated individually (approx. 100 mL/kg/24h for maintenance) | Continuous intravenous infusion | Ensure cardiorespiratory stability; monitor for signs of fluid overload. |
| 11-15 kg | 1000 mL + 50 mL for each kg over 10 kg per 24 hours | Continuous intravenous infusion | Corresponds to approximately 40 to 52 mL/hour maintenance rate. |
| 16-20 kg | 1000 mL + 50 mL for each kg over 10 kg per 24 hours | Continuous intravenous infusion | Corresponds to approximately 52 to 62 mL/hour maintenance rate. Adjust based on specific metabolic needs. |
Formulation
Purpose
Used for fluid and electrolyte replenishment, extracellular fluid volume replacement, and as an alkalinizing agent in patients with mild metabolic acidosis.
Generic Name
Multiple Electrolytes InjectionScheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.