Phenobarbital
Acts as a non-selective CNS depressant. One of the oldest and most widely used seizure medications globally, especially in resource-limited settings.
Dosage by Body Weight
Maintenance dose for children: 3-5 mg/kg per day. Requires therapeutic drug monitoring (TDM).
- Body Weight
- 5-10 kg
- Dose
- 15 mg to 30 mg total daily
- Frequency
- Once daily or divided
- Tracking Notes
- May cause significant drowsiness and behavioral changes.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| 5-10 kg | 15 mg to 30 mg total daily | Once daily or divided | May cause significant drowsiness and behavioral changes. |
Formulation
Purpose
Barbiturate used as an antiepileptic to control seizures and as a sedative.
Generic Name
Phenobarbital SodiumBranded Drug Names
Phenobarbital is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:
Scheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.
Alternatives
Safety Advice
Alcohol
UNSAFEPhenobarbital: Alcohol can significantly increase drowsiness, dizziness, breathing problems, or seizure risk. Avoid alcohol unless a specialist says otherwise.
Pregnancy
CAUTIONPhenobarbital: Use in pregnancy only under specialist advice because seizure control and fetal risks must be carefully balanced.
Breast Feeding
SAFE IF PRESCRIBEDPhenobarbital: May pass into breast milk and can cause infant drowsiness or feeding issues. Use only with healthcare provider guidance.
Driving
CAUTIONPhenobarbital: Can cause drowsiness, slowed reaction time, dizziness, or blurred vision. Avoid driving until you know how it affects you.
Liver
CAUTIONPhenobarbital: Some anti-seizure medicines can affect liver function and may require blood tests or dose adjustments.
Kidney
CAUTIONPhenobarbital: Some anti-seizure medicines require dose adjustment in kidney impairment. Use under medical supervision.