Phenicol Syrup
Phenicol Syrup contains Chloramphenicol (as palmitate), a broad-spectrum antibiotic that inhibits bacterial protein synthesis. Because of potential serious side effects, including bone marrow toxicity and Gray Baby Syndrome, it is reserved for severe infections where safer alternatives are not available.
Dosage by Body Weight
Standard pediatric dose is 50 mg/kg/day divided into 4 doses (every 6 hours). Dosage calculations below are based on a standard 125 mg/5 mL concentration of Chloramphenicol Palmitate. Always consult a pediatrician before administration.
- Body Weight
- Below 5 kg
- Dose
- Not routine
- Frequency
- Use only if prescribed
- Tracking Notes
- Extremely high risk of Gray Baby Syndrome in newborns and premature infants. Requires strict therapeutic drug monitoring.
- Body Weight
- 5-7 kg
- Dose
- 2.5 mL to 3 mL (62.5 mg to 75 mg)
- Frequency
- Every 6 hours (4 times daily)
- Tracking Notes
- Monitor complete blood counts regularly if treatment exceeds 10 days.
- Body Weight
- 8-10 kg
- Dose
- 4 mL to 5 mL (100 mg to 125 mg)
- Frequency
- Every 6 hours (4 times daily)
- Tracking Notes
- Ensure exact measurement using a syringe or dosing spoon.
- Body Weight
- 11-15 kg
- Dose
- 5.5 mL to 7.5 mL (137.5 mg to 187.5 mg)
- Frequency
- Every 6 hours (4 times daily)
- Tracking Notes
- Administer on an empty stomach (1 hour before or 2 hours after meals) for optimal absorption.
- Body Weight
- 16-20 kg
- Dose
- 8 mL to 10 mL (200 mg to 250 mg)
- Frequency
- Every 6 hours (4 times daily)
- Tracking Notes
- Complete the entire prescribed course even if symptoms resolve earlier.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Not routine | Use only if prescribed | Extremely high risk of Gray Baby Syndrome in newborns and premature infants. Requires strict therapeutic drug monitoring. |
| 5-7 kg | 2.5 mL to 3 mL (62.5 mg to 75 mg) | Every 6 hours (4 times daily) | Monitor complete blood counts regularly if treatment exceeds 10 days. |
| 8-10 kg | 4 mL to 5 mL (100 mg to 125 mg) | Every 6 hours (4 times daily) | Ensure exact measurement using a syringe or dosing spoon. |
| 11-15 kg | 5.5 mL to 7.5 mL (137.5 mg to 187.5 mg) | Every 6 hours (4 times daily) | Administer on an empty stomach (1 hour before or 2 hours after meals) for optimal absorption. |
| 16-20 kg | 8 mL to 10 mL (200 mg to 250 mg) | Every 6 hours (4 times daily) | Complete the entire prescribed course even if symptoms resolve earlier. |
Formulation
Purpose
Treatment of severe, life-threatening bacterial infections such as typhoid fever, bacterial meningitis, and rickettsial infections when other safer antibiotics are ineffective or contraindicated.
Generic Name
Chloramphenicol PalmitateScheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.