Periactin
Periactin (cyproheptadine) is a first-generation antihistamine with anticholinergic, antiserotonergic, and local anesthetic properties. It works by competing with free histamine for binding at H1-receptor sites and blocking serotonin receptors in the appetite center of the brain.
Dosage by Body Weight
Dosing is typically based on age and response. It is strictly contraindicated in newborn or premature infants and not recommended for children under 2 years of age due to safety concerns.
- Body Weight
- Below 5 kg
- Dose
- Not recommended
- Frequency
- Do not use
- Tracking Notes
- Contraindicated in newborns and premature infants.
- Body Weight
- 5-7 kg
- Dose
- Not recommended
- Frequency
- Do not use
- Tracking Notes
- Safety and efficacy have not been established for children under 2 years of age.
- Body Weight
- 8-10 kg
- Dose
- Not recommended
- Frequency
- Do not use
- Tracking Notes
- Avoid use unless explicitly directed and supervised by a pediatrician.
- Body Weight
- 11-15 kg
- Dose
- 2 mg (5 mL of syrup or 1/2 tablet)
- Frequency
- 2 to 3 times daily
- Tracking Notes
- Only for children aged 2 years or older. Do not exceed a maximum of 12 mg/day.
- Body Weight
- 16-20 kg
- Dose
- 2 mg (5 mL of syrup or 1/2 tablet)
- Frequency
- 2 to 3 times daily
- Tracking Notes
- Only for children aged 2 years or older. Do not exceed a maximum of 12 mg/day.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Not recommended | Do not use | Contraindicated in newborns and premature infants. |
| 5-7 kg | Not recommended | Do not use | Safety and efficacy have not been established for children under 2 years of age. |
| 8-10 kg | Not recommended | Do not use | Avoid use unless explicitly directed and supervised by a pediatrician. |
| 11-15 kg | 2 mg (5 mL of syrup or 1/2 tablet) | 2 to 3 times daily | Only for children aged 2 years or older. Do not exceed a maximum of 12 mg/day. |
| 16-20 kg | 2 mg (5 mL of syrup or 1/2 tablet) | 2 to 3 times daily | Only for children aged 2 years or older. Do not exceed a maximum of 12 mg/day. |
Formulation
TabletSyrup
Purpose
Relief of allergic symptoms such as runny nose, sneezing, itchy and watery eyes, and hives. It is also used off-label as an appetite stimulant.
Generic Name
CyproheptadineScheduled Drug
No. This medicine is generally not treated as a scheduled/prescription-only drug in common consumer references, but local rules may vary.