Oflox
Oflox contains Ofloxacin, a broad-spectrum fluoroquinolone antibiotic. It works by inhibiting bacterial DNA gyrase and topoisomerase IV, which are essential enzymes for bacterial DNA replication, transcription, and repair. It is effective against both Gram-positive and Gram-negative bacteria.
Dosage by Body Weight
Adults: Typically 200 mg to 400 mg orally every 12 hours depending on the severity and type of infection. Pediatric dosing is strictly weight-based and reserved for specific complex infections. Take with or without food. Avoid taking antacids, calcium, or iron supplements within 2 hours of this medication.
- Body Weight
- Below 5 kg
- Dose
- Not recommended
- Frequency
- Use only if specifically prescribed by a specialist
- Tracking Notes
- Safety and efficacy in infants under 6 months have not been established.
- Body Weight
- 5-7 kg
- Dose
- 37.5 mg to 52.5 mg (approx. 3.75 ml to 5 ml of 50 mg/5 ml suspension)
- Frequency
- Every 12 hours
- Tracking Notes
- Pediatric use of fluoroquinolones is restricted to specific indications due to potential musculoskeletal risks.
- Body Weight
- 8-10 kg
- Dose
- 60 mg to 75 mg (approx. 6 ml to 7.5 ml of 50 mg/5 ml suspension)
- Frequency
- Every 12 hours
- Tracking Notes
- Ensure proper dose measurement using a calibrated syringe.
- Body Weight
- 11-15 kg
- Dose
- 82.5 mg to 112.5 mg (approx. 4.1 ml to 5.6 ml of 100 mg/5 ml suspension)
- Frequency
- Every 12 hours
- Tracking Notes
- Monitor closely for any signs of joint pain or tendon tenderness.
- Body Weight
- 16-20 kg
- Dose
- 120 mg to 150 mg (approx. 6 ml to 7.5 ml of 100 mg/5 ml suspension)
- Frequency
- Every 12 hours
- Tracking Notes
- Ensure child drinks plenty of fluids to avoid crystalluria.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Not recommended | Use only if specifically prescribed by a specialist | Safety and efficacy in infants under 6 months have not been established. |
| 5-7 kg | 37.5 mg to 52.5 mg (approx. 3.75 ml to 5 ml of 50 mg/5 ml suspension) | Every 12 hours | Pediatric use of fluoroquinolones is restricted to specific indications due to potential musculoskeletal risks. |
| 8-10 kg | 60 mg to 75 mg (approx. 6 ml to 7.5 ml of 50 mg/5 ml suspension) | Every 12 hours | Ensure proper dose measurement using a calibrated syringe. |
| 11-15 kg | 82.5 mg to 112.5 mg (approx. 4.1 ml to 5.6 ml of 100 mg/5 ml suspension) | Every 12 hours | Monitor closely for any signs of joint pain or tendon tenderness. |
| 16-20 kg | 120 mg to 150 mg (approx. 6 ml to 7.5 ml of 100 mg/5 ml suspension) | Every 12 hours | Ensure child drinks plenty of fluids to avoid crystalluria. |
Formulation
Purpose
Used to treat a variety of bacterial infections, including acute bacterial exacerbations of chronic bronchitis, community-acquired pneumonia, uncomplicated skin infections, nongonococcal urethritis, pelvic inflammatory disease, and complicated urinary tract infections.
Generic Name
OfloxacinScheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.