Mitigo
Mitigo (morphine sulfate injection) is a preservative-free opioid agonist indicated for the management of severe, intractable chronic pain. It is administered via an implantable infusion pump directly into the epidural or intrathecal space.
Dosage by Body Weight
Administered only epidurally or intrathecally. Dosage must be highly individualized. Starting doses depend on prior daily opioid exposure. Must be administered under the supervision of a qualified physician experienced in intrathecal/epidural administration.
- Body Weight
- Below 5 kg
- Dose
- Not recommended
- Frequency
- N/A
- Tracking Notes
- Safety and efficacy have not been established in pediatric patients.
- Body Weight
- 5-7 kg
- Dose
- Not recommended
- Frequency
- N/A
- Tracking Notes
- Safety and efficacy have not been established in pediatric patients.
- Body Weight
- 8-10 kg
- Dose
- Not recommended
- Frequency
- N/A
- Tracking Notes
- Safety and efficacy have not been established in pediatric patients.
- Body Weight
- 11-15 kg
- Dose
- Not recommended
- Frequency
- N/A
- Tracking Notes
- Safety and efficacy have not been established in pediatric patients.
- Body Weight
- 16-20 kg
- Dose
- Not recommended
- Frequency
- N/A
- Tracking Notes
- Safety and efficacy have not been established in pediatric patients.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Not recommended | N/A | Safety and efficacy have not been established in pediatric patients. |
| 5-7 kg | Not recommended | N/A | Safety and efficacy have not been established in pediatric patients. |
| 8-10 kg | Not recommended | N/A | Safety and efficacy have not been established in pediatric patients. |
| 11-15 kg | Not recommended | N/A | Safety and efficacy have not been established in pediatric patients. |
| 16-20 kg | Not recommended | N/A | Safety and efficacy have not been established in pediatric patients. |
Formulation
Purpose
Management of intractable chronic pain severe enough to require epidural or intrathecal opioid analgesia, when alternative pain management therapies are inadequate.
Generic Name
Morphine sulfate (preservative-free)Scheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.