Milrinone
A phosphodiesterase inhibitor that increases the heart's pumping strength and decreases pulmonary vascular resistance (inotrope and vasodilator).
Dosage by Body Weight
Pediatric loading dose: 50 mcg/kg over 10-60 mins, followed by a continuous infusion of 0.25 to 0.75 mcg/kg/min.
- Body Weight
- Infants/Children
- Dose
- Continuous Infusion
- Frequency
- Constant
- Tracking Notes
- Monitor blood pressure closely for hypotension (low BP).
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Infants/Children | Continuous Infusion | Constant | Monitor blood pressure closely for hypotension (low BP). |
Formulation
Purpose
Short-term management of acute heart failure or post-cardiac surgery support.
Generic Name
Milrinone LactateBranded Drug Names
Milrinone is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:
Scheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.
Alternatives
Safety Advice
Alcohol
CAUTIONMilrinone: Alcohol can increase dizziness, low blood pressure, dehydration, or heart rhythm symptoms. Avoid or limit alcohol.
Pregnancy
CAUTIONMilrinone: Use in pregnancy only when prescribed; some heart or blood pressure medicines are not suitable during pregnancy.
Breast Feeding
SAFE IF PRESCRIBEDMilrinone: Use while breastfeeding only with healthcare provider guidance, as infant monitoring may be needed.
Driving
CAUTIONMilrinone: May cause dizziness, faintness, tiredness, or blurred vision, especially when starting or changing dose. Avoid driving if affected.
Liver
CAUTIONMilrinone: Liver disease may alter medicine handling and increase side effects. Use with medical supervision.
Kidney
CAUTIONMilrinone: Kidney function and electrolytes may need monitoring, especially with diuretics, ACE inhibitors, ARBs, or digoxin.