Milrinone

A phosphodiesterase inhibitor that increases the heart's pumping strength and decreases pulmonary vascular resistance (inotrope and vasodilator).

Dosage by Body Weight

Pediatric loading dose: 50 mcg/kg over 10-60 mins, followed by a continuous infusion of 0.25 to 0.75 mcg/kg/min.

  1. Body Weight
    Infants/Children
    Dose
    Continuous Infusion
    Frequency
    Constant
    Tracking Notes
    Monitor blood pressure closely for hypotension (low BP).

Formulation

Injection

Purpose

Short-term management of acute heart failure or post-cardiac surgery support.

Generic Name

Milrinone Lactate

Branded Drug Names

Milrinone is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:

Scheduled Drug

Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.

Alternatives

Safety Advice

Alcohol

CAUTION

Milrinone: Alcohol can increase dizziness, low blood pressure, dehydration, or heart rhythm symptoms. Avoid or limit alcohol.

Pregnancy

CAUTION

Milrinone: Use in pregnancy only when prescribed; some heart or blood pressure medicines are not suitable during pregnancy.

Breast Feeding

SAFE IF PRESCRIBED

Milrinone: Use while breastfeeding only with healthcare provider guidance, as infant monitoring may be needed.

Driving

CAUTION

Milrinone: May cause dizziness, faintness, tiredness, or blurred vision, especially when starting or changing dose. Avoid driving if affected.

Liver

CAUTION

Milrinone: Liver disease may alter medicine handling and increase side effects. Use with medical supervision.

Kidney

CAUTION

Milrinone: Kidney function and electrolytes may need monitoring, especially with diuretics, ACE inhibitors, ARBs, or digoxin.

Disclaimer: This information is for educational purposes only. WHO references and weight bands are simplified for tracking and must not replace medical advice. Always consult with a healthcare professional before starting or changing any medication.