Methimazole
Inhibits the enzyme thyroid peroxidase, which prevents the thyroid gland from producing thyroid hormone.
Dosage by Body Weight
Pediatric initial dose: 0.4 mg/kg/day. Maintenance is 50% of the initial dose.
- Body Weight
- 20-30 kg
- Dose
- 10 mg
- Frequency
- Once daily
- Tracking Notes
- Monitor for sore throat or fever (signs of low white cell count).
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| 20-30 kg | 10 mg | Once daily | Monitor for sore throat or fever (signs of low white cell count). |
Formulation
Purpose
Treatment of hyperthyroidism (Graves' disease) in children.
Generic Name
MethimazoleBranded Drug Names
Methimazole is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:
Scheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.
Alternatives
Safety Advice
Alcohol
CAUTIONMethimazole: Alcohol can affect blood sugar, hormones, or dehydration risk. Avoid or limit alcohol and follow your clinician advice.
Pregnancy
SAFE IF PRESCRIBEDMethimazole: Use during pregnancy only with specialist guidance; dose needs may change and monitoring is important.
Breast Feeding
SAFE IF PRESCRIBEDMethimazole: Use while breastfeeding only as directed; endocrine treatments often require ongoing clinical monitoring.
Driving
CAUTIONMethimazole: May affect alertness indirectly through low blood sugar, dizziness, or hormone imbalance. Avoid driving if symptoms occur.
Liver
CAUTIONMethimazole: Use with medical guidance in liver disease, especially when metabolism or blood sugar control may be affected.
Kidney
CAUTIONMethimazole: Kidney disease can change dosing or monitoring needs for several endocrine medicines.