Lomofen
Lomofen is an antidiarrheal combination medication containing Diphenoxylate and Atropine. Diphenoxylate is an opioid derivative that works by slowing down gut motility, which decreases the frequency of bowel movements. Atropine, an anticholinergic, is present in a tiny, sub-therapeutic dose to prevent abuse and deliberate overdose of the diphenoxylate component.
Dosage by Body Weight
For adults, the usual initial dose is 2 tablets taken 3 to 4 times daily. Once diarrhea is controlled, the dosage should be reduced to a maintenance dose (e.g., 2 tablets daily) as recommended by a doctor. This medication is contraindicated in children under 2 years of age and generally not recommended for pediatric use due to the risk of respiratory depression and atropine toxicity.
- Body Weight
- Below 5 kg
- Dose
- Contraindicated
- Frequency
- Do not administer
- Tracking Notes
- Strictly contraindicated in infants due to severe risk of breathing difficulties and atropine poisoning.
- Body Weight
- 5-7 kg
- Dose
- Contraindicated
- Frequency
- Do not administer
- Tracking Notes
- Strictly contraindicated in young children.
- Body Weight
- 8-10 kg
- Dose
- Contraindicated
- Frequency
- Do not administer
- Tracking Notes
- Not recommended for children under 2 years of age.
- Body Weight
- 11-15 kg
- Dose
- Not recommended
- Frequency
- Avoid use
- Tracking Notes
- High risk of adverse effects; use alternative rehydration therapies instead.
- Body Weight
- 16-20 kg
- Dose
- Not recommended
- Frequency
- Avoid use
- Tracking Notes
- Should only be used in older children if explicitly prescribed and supervised by a pediatrician.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Contraindicated | Do not administer | Strictly contraindicated in infants due to severe risk of breathing difficulties and atropine poisoning. |
| 5-7 kg | Contraindicated | Do not administer | Strictly contraindicated in young children. |
| 8-10 kg | Contraindicated | Do not administer | Not recommended for children under 2 years of age. |
| 11-15 kg | Not recommended | Avoid use | High risk of adverse effects; use alternative rehydration therapies instead. |
| 16-20 kg | Not recommended | Avoid use | Should only be used in older children if explicitly prescribed and supervised by a pediatrician. |
Formulation
Purpose
Symptomatic relief of acute diarrhea in adults.
Generic Name
Diphenoxylate Hydrochloride + Atropine SulphateScheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.