Lariago
Lariago contains Chloroquine, an antiparasitic and anti-inflammatory medication. It works by increasing the pH inside the parasite's acid vesicles, disrupting its growth and survival. Due to its narrow safety margin, precise dosing is critical to avoid severe toxicity.
Dosage by Body Weight
Dosing is highly individualized and must be based strictly on body weight (typically calculated as 25 mg/kg of chloroquine base administered over 3 days for malaria treatment). To minimize stomach upset, it should always be taken with food or milk.
- Body Weight
- Below 5 kg
- Dose
- Requires precise clinical calculation (approx. 10 mg/kg base initially)
- Frequency
- Under strict pediatric supervision
- Tracking Notes
- High risk of toxicity in infants. Do not self-administer.
- Body Weight
- 5-7 kg
- Dose
- 50 mg to 70 mg base initial dose, then 25 mg to 35 mg base
- Frequency
- At 0, 6, 24, and 48 hours
- Tracking Notes
- Preferably administered as oral suspension (50 mg base per 5 ml) for accurate dosing.
- Body Weight
- 8-10 kg
- Dose
- 80 mg to 100 mg base initial dose, then 40 mg to 50 mg base
- Frequency
- At 0, 6, 24, and 48 hours
- Tracking Notes
- Corresponds to approximately 8 to 10 ml of standard syrup for the first dose.
- Body Weight
- 11-15 kg
- Dose
- 110 mg to 150 mg base initial dose, then 55 mg to 75 mg base
- Frequency
- At 0, 6, 24, and 48 hours
- Tracking Notes
- Monitor closely for side effects like nausea, vomiting, or dizziness.
- Body Weight
- 16-20 kg
- Dose
- 160 mg to 200 mg base initial dose, then 80 mg to 100 mg base
- Frequency
- At 0, 6, 24, and 48 hours
- Tracking Notes
- A fraction of a tablet may be used if suspension is unavailable, provided it can be split accurately.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Requires precise clinical calculation (approx. 10 mg/kg base initially) | Under strict pediatric supervision | High risk of toxicity in infants. Do not self-administer. |
| 5-7 kg | 50 mg to 70 mg base initial dose, then 25 mg to 35 mg base | At 0, 6, 24, and 48 hours | Preferably administered as oral suspension (50 mg base per 5 ml) for accurate dosing. |
| 8-10 kg | 80 mg to 100 mg base initial dose, then 40 mg to 50 mg base | At 0, 6, 24, and 48 hours | Corresponds to approximately 8 to 10 ml of standard syrup for the first dose. |
| 11-15 kg | 110 mg to 150 mg base initial dose, then 55 mg to 75 mg base | At 0, 6, 24, and 48 hours | Monitor closely for side effects like nausea, vomiting, or dizziness. |
| 16-20 kg | 160 mg to 200 mg base initial dose, then 80 mg to 100 mg base | At 0, 6, 24, and 48 hours | A fraction of a tablet may be used if suspension is unavailable, provided it can be split accurately. |
Formulation
Purpose
Treatment and prevention of malaria, extraintestinal amoebiasis, and management of autoimmune conditions like rheumatoid arthritis and lupus erythematosus.
Generic Name
Chloroquine PhosphateScheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.