Kezol
Kezol is an antifungal medication containing Ketoconazole. It works by inhibiting the synthesis of ergosterol, a vital component of fungal cell membranes, thereby disrupting membrane integrity and halting fungal growth. It is available in topical formulations for localized skin and scalp issues and in oral tablet form for severe, systemic fungal infections when alternative therapies are not tolerated or available.
Dosage by Body Weight
Topical: Apply cream to the affected area 1 to 2 times daily. Shampoo should be applied to wet hair, massaged, left for 3 to 5 minutes, and rinsed. Oral: The standard adult dosage for oral tablets is 200 mg to 400 mg once daily, taken with food to maximize absorption. Oral Ketoconazole carries a risk of hepatotoxicity and should be used under strict medical supervision with regular liver function monitoring.
- Body Weight
- Below 5 kg
- Dose
- Not recommended
- Frequency
- Not applicable
- Tracking Notes
- Oral administration is not recommended. Topical formulations must only be used under direct pediatric supervision.
- Body Weight
- 5-7 kg
- Dose
- Not recommended
- Frequency
- Not applicable
- Tracking Notes
- Systemic use is highly restricted in infants due to risk of liver toxicity. Consult a specialist.
- Body Weight
- 8-10 kg
- Dose
- Not routine / 3.3 to 6.6 mg/kg
- Frequency
- Once daily
- Tracking Notes
- Use only if absolutely necessary and alternative options are unavailable. Requires close liver function monitoring.
- Body Weight
- 11-15 kg
- Dose
- 50 mg
- Frequency
- Once daily
- Tracking Notes
- To be administered under strict medical supervision. Dosage adjusted based on clinical response and tolerability.
- Body Weight
- 16-20 kg
- Dose
- 50 mg to 100 mg
- Frequency
- Once daily
- Tracking Notes
- Requires monitoring of hepatic function tests before and during the treatment course.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Not recommended | Not applicable | Oral administration is not recommended. Topical formulations must only be used under direct pediatric supervision. |
| 5-7 kg | Not recommended | Not applicable | Systemic use is highly restricted in infants due to risk of liver toxicity. Consult a specialist. |
| 8-10 kg | Not routine / 3.3 to 6.6 mg/kg | Once daily | Use only if absolutely necessary and alternative options are unavailable. Requires close liver function monitoring. |
| 11-15 kg | 50 mg | Once daily | To be administered under strict medical supervision. Dosage adjusted based on clinical response and tolerability. |
| 16-20 kg | 50 mg to 100 mg | Once daily | Requires monitoring of hepatic function tests before and during the treatment course. |
Formulation
Purpose
Treatment of superficial and systemic fungal infections, including dandruff, seborrheic dermatitis, tinea infections (ringworm, athlete's foot, jock itch), and pityriasis versicolor.
Generic Name
KetoconazoleScheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.