Ivelest
Ivelest contains Sivelestat, which is a selective inhibitor of neutrophil elastase. It helps prevent lung tissue damage and improves respiratory function in critically ill patients suffering from severe inflammatory conditions of the lungs.
Dosage by Body Weight
Administered strictly in an ICU or critical care setting as a continuous intravenous infusion. The standard adult dose is 0.2 mg/kg/hour. Pediatric dosing must be precisely determined by a specialist.
- Body Weight
- Below 5 kg
- Dose
- 0.2 mg/kg/hour
- Frequency
- Continuous IV infusion
- Tracking Notes
- Must be administered under strict intensive care monitoring and calculated precisely by a neonatologist or pediatrician.
- Body Weight
- 5-7 kg
- Dose
- 1.0 to 1.4 mg/hour
- Frequency
- Continuous IV infusion
- Tracking Notes
- Infusion rate calculated based on the standard 0.2 mg/kg/hour guideline.
- Body Weight
- 8-10 kg
- Dose
- 1.6 to 2.0 mg/hour
- Frequency
- Continuous IV infusion
- Tracking Notes
- Infusion rate calculated based on the standard 0.2 mg/kg/hour guideline.
- Body Weight
- 11-15 kg
- Dose
- 2.2 to 3.0 mg/hour
- Frequency
- Continuous IV infusion
- Tracking Notes
- Infusion rate calculated based on the standard 0.2 mg/kg/hour guideline.
- Body Weight
- 16-20 kg
- Dose
- 3.2 to 4.0 mg/hour
- Frequency
- Continuous IV infusion
- Tracking Notes
- Infusion rate calculated based on the standard 0.2 mg/kg/hour guideline.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | 0.2 mg/kg/hour | Continuous IV infusion | Must be administered under strict intensive care monitoring and calculated precisely by a neonatologist or pediatrician. |
| 5-7 kg | 1.0 to 1.4 mg/hour | Continuous IV infusion | Infusion rate calculated based on the standard 0.2 mg/kg/hour guideline. |
| 8-10 kg | 1.6 to 2.0 mg/hour | Continuous IV infusion | Infusion rate calculated based on the standard 0.2 mg/kg/hour guideline. |
| 11-15 kg | 2.2 to 3.0 mg/hour | Continuous IV infusion | Infusion rate calculated based on the standard 0.2 mg/kg/hour guideline. |
| 16-20 kg | 3.2 to 4.0 mg/hour | Continuous IV infusion | Infusion rate calculated based on the standard 0.2 mg/kg/hour guideline. |
Formulation
Injection
Purpose
Used to treat acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) associated with systemic inflammatory response syndrome (SIRS).
Generic Name
Sivelestat SodiumScheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.