Insulin Lispro
Insulin lispro is a rapid-acting recombinant human insulin analog. It begins to work approximately 15 minutes after injection, peaks in about 1 hour, and keeps working for 2 to 4 hours. It works by stimulating peripheral glucose uptake and inhibiting hepatic glucose production.
Dosage by Body Weight
Dosage must be highly individualized based on the patient's metabolic needs, blood glucose monitoring results, and glycemic control goals. It is typically administered subcutaneously within 15 minutes before a meal or immediately after a meal.
- Body Weight
- Below 5 kg
- Dose
- Individualized
- Frequency
- With meals or via continuous infusion
- Tracking Notes
- Extremely high risk of hypoglycemia. Dosing must be determined under strict pediatric endocrinology supervision.
- Body Weight
- 5-7 kg
- Dose
- 0.1 to 0.2 units/kg per meal
- Frequency
- Within 15 minutes before meals
- Tracking Notes
- Adjust dose carefully based on blood glucose monitoring and carbohydrate intake.
- Body Weight
- 8-10 kg
- Dose
- 0.1 to 0.2 units/kg per meal
- Frequency
- Within 15 minutes before meals
- Tracking Notes
- Dose titration should be done slowly in increments of 0.5 to 1 unit.
- Body Weight
- 11-15 kg
- Dose
- 0.1 to 0.25 units/kg per meal
- Frequency
- Within 15 minutes before meals
- Tracking Notes
- Monitor blood glucose frequently. Ensure adequate carbohydrate intake immediately following injection.
- Body Weight
- 16-20 kg
- Dose
- 0.1 to 0.25 units/kg per meal
- Frequency
- Within 15 minutes before meals
- Tracking Notes
- Dose varies significantly depending on physical activity levels and total daily carbohydrate intake.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Individualized | With meals or via continuous infusion | Extremely high risk of hypoglycemia. Dosing must be determined under strict pediatric endocrinology supervision. |
| 5-7 kg | 0.1 to 0.2 units/kg per meal | Within 15 minutes before meals | Adjust dose carefully based on blood glucose monitoring and carbohydrate intake. |
| 8-10 kg | 0.1 to 0.2 units/kg per meal | Within 15 minutes before meals | Dose titration should be done slowly in increments of 0.5 to 1 unit. |
| 11-15 kg | 0.1 to 0.25 units/kg per meal | Within 15 minutes before meals | Monitor blood glucose frequently. Ensure adequate carbohydrate intake immediately following injection. |
| 16-20 kg | 0.1 to 0.25 units/kg per meal | Within 15 minutes before meals | Dose varies significantly depending on physical activity levels and total daily carbohydrate intake. |
Formulation
Purpose
Used to improve glycemic control in adults and pediatric patients with diabetes mellitus (Type 1 and Type 2).
Generic Name
Insulin LisproBranded Drug Names
Insulin Lispro is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:
Scheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.