Gris-PEG
Gris-PEG is an oral antifungal medication containing ultramicrosize griseofulvin. The ultramicrosize formulation has enhanced absorption compared to standard microsize griseofulvin, allowing for lower therapeutic doses. It works by binding to keratin in the body to prevent fungal cells from multiplying and spreading to new skin, hair, or nail growth.
Dosage by Body Weight
Must be taken orally, preferably with a high-fat meal (such as whole milk, cheese, or ice cream) to significantly increase absorption. Treatment duration varies widely depending on the infection site (e.g., 2 to 4 weeks for skin infections, 4 to 6 weeks for scalp infections, and up to several months for nail infections). Complete the full prescribed course.
- Body Weight
- Below 5 kg
- Dose
- Not routine / Not recommended
- Frequency
- Use only if prescribed by a specialist
- Tracking Notes
- Safety and efficacy in children under 2 years of age or weighing less than 13.6 kg have not been established.
- Body Weight
- 5-7 kg
- Dose
- Not routine / Consult pediatrician
- Frequency
- Use only if prescribed
- Tracking Notes
- Oral tablet formulation is highly difficult to dose accurately at this weight. Griseofulvin microsize oral suspension is usually preferred if treatment is deemed necessary.
- Body Weight
- 8-10 kg
- Dose
- Consult pediatrician
- Frequency
- Use only if prescribed
- Tracking Notes
- Typically requires an alternative pediatric liquid formulation of griseofulvin, as splitting the 125 mg Gris-PEG tablet for this weight is imprecise.
- Body Weight
- 11-15 kg
- Dose
- 125 mg daily
- Frequency
- Once daily
- Tracking Notes
- Approximate pediatric dose. The standard pediatric dosing for Gris-PEG in children weighing 13.6 to 23 kg (30 to 50 lbs) is 125 mg to 187.5 mg daily. Always administer with a high-fat meal.
- Body Weight
- 16-20 kg
- Dose
- 125 mg to 187.5 mg daily
- Frequency
- Once daily
- Tracking Notes
- Calculated based on standard clinical guidelines for ultramicrosize formulation (approximately 7.3 mg/kg/day). Must be taken with a high-fat meal.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Not routine / Not recommended | Use only if prescribed by a specialist | Safety and efficacy in children under 2 years of age or weighing less than 13.6 kg have not been established. |
| 5-7 kg | Not routine / Consult pediatrician | Use only if prescribed | Oral tablet formulation is highly difficult to dose accurately at this weight. Griseofulvin microsize oral suspension is usually preferred if treatment is deemed necessary. |
| 8-10 kg | Consult pediatrician | Use only if prescribed | Typically requires an alternative pediatric liquid formulation of griseofulvin, as splitting the 125 mg Gris-PEG tablet for this weight is imprecise. |
| 11-15 kg | 125 mg daily | Once daily | Approximate pediatric dose. The standard pediatric dosing for Gris-PEG in children weighing 13.6 to 23 kg (30 to 50 lbs) is 125 mg to 187.5 mg daily. Always administer with a high-fat meal. |
| 16-20 kg | 125 mg to 187.5 mg daily | Once daily | Calculated based on standard clinical guidelines for ultramicrosize formulation (approximately 7.3 mg/kg/day). Must be taken with a high-fat meal. |
Formulation
Purpose
Used to treat fungal infections of the skin, hair, and nails, including ringworm (tinea capitis, tinea corporis), athlete's foot (tinea pedis), jock itch (tinea cruris), and fungal nail infections (onychomycosis/tinea unguium).
Generic Name
Griseofulvin ultramicrosizeScheduled Drug
No. This medicine is generally not treated as a scheduled/prescription-only drug in common consumer references, but local rules may vary.