Epaned
Epaned (enalapril maleate) is an angiotensin-converting enzyme (ACE) inhibitor. It works by relaxing blood vessels, lowering blood pressure, and increasing the supply of blood and oxygen to the heart. It is formulated as an oral solution, which is particularly beneficial for pediatric patients and adults who have difficulty swallowing pills.
Dosage by Body Weight
For pediatric patients with hypertension, the recommended starting dose is 0.08 mg/kg (up to 5 mg) administered once daily. Dosage should be adjusted based on blood pressure response. It is not recommended for neonates (under 1 month of age) or pediatric patients with severe renal impairment.
- Body Weight
- Below 5 kg
- Dose
- Not routine
- Frequency
- Use only if prescribed
- Tracking Notes
- Safety and effectiveness have not been established in infants under 1 month of age. Use with extreme caution.
- Body Weight
- 5-7 kg
- Dose
- 0.4 mg to 0.56 mg (0.4 mL to 0.56 mL of 1 mg/mL solution)
- Frequency
- Once daily
- Tracking Notes
- Calculated based on the standard pediatric starting dose of 0.08 mg/kg daily. Adjust according to clinical response.
- Body Weight
- 8-10 kg
- Dose
- 0.64 mg to 0.8 mg (0.64 mL to 0.8 mL of 1 mg/mL solution)
- Frequency
- Once daily
- Tracking Notes
- Calculated based on the standard pediatric starting dose of 0.08 mg/kg daily. Adjust according to clinical response.
- Body Weight
- 11-15 kg
- Dose
- 0.88 mg to 1.2 mg (0.88 mL to 1.2 mL of 1 mg/mL solution)
- Frequency
- Once daily
- Tracking Notes
- Calculated based on the standard pediatric starting dose of 0.08 mg/kg daily. Adjust according to clinical response.
- Body Weight
- 16-20 kg
- Dose
- 1.28 mg to 1.6 mg (1.28 mL to 1.6 mL of 1 mg/mL solution)
- Frequency
- Once daily
- Tracking Notes
- Calculated based on the standard pediatric starting dose of 0.08 mg/kg daily. Adjust according to clinical response.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Not routine | Use only if prescribed | Safety and effectiveness have not been established in infants under 1 month of age. Use with extreme caution. |
| 5-7 kg | 0.4 mg to 0.56 mg (0.4 mL to 0.56 mL of 1 mg/mL solution) | Once daily | Calculated based on the standard pediatric starting dose of 0.08 mg/kg daily. Adjust according to clinical response. |
| 8-10 kg | 0.64 mg to 0.8 mg (0.64 mL to 0.8 mL of 1 mg/mL solution) | Once daily | Calculated based on the standard pediatric starting dose of 0.08 mg/kg daily. Adjust according to clinical response. |
| 11-15 kg | 0.88 mg to 1.2 mg (0.88 mL to 1.2 mL of 1 mg/mL solution) | Once daily | Calculated based on the standard pediatric starting dose of 0.08 mg/kg daily. Adjust according to clinical response. |
| 16-20 kg | 1.28 mg to 1.6 mg (1.28 mL to 1.6 mL of 1 mg/mL solution) | Once daily | Calculated based on the standard pediatric starting dose of 0.08 mg/kg daily. Adjust according to clinical response. |
Formulation
Purpose
Treatment of hypertension (high blood pressure) in adults and pediatric patients older than 1 month, and for the treatment of heart failure or asymptomatic left ventricular dysfunction in adults.
Generic Name
Enalapril maleateScheduled Drug
No. This medicine is generally not treated as a scheduled/prescription-only drug in common consumer references, but local rules may vary.