Entamizole
Entamizole is a combination antimicrobial medication containing Metronidazole (a systemic amoebicide and antibacterial) and Diloxanide Furoate (a luminal amoebicide). It is highly effective in treating amoebic dysentery by eradicating Entamoeba histolytica in both the intestinal lumen and tissue walls.
Dosage by Body Weight
Take orally with or after food to prevent stomach upset. Do not consume alcohol during therapy and for at least 48 hours after the last dose to avoid a disulfiram-like reaction. Complete the full prescribed course even if symptoms resolve early.
- Body Weight
- Below 5 kg
- Dose
- Not recommended / Not routine
- Frequency
- Use only if explicitly prescribed by a pediatrician
- Tracking Notes
- Safety and efficacy in infants under 5 kg or below 6 months have not been fully established.
- Body Weight
- 5-7 kg
- Dose
- 1.25 ml to 2.5 ml of pediatric suspension (100mg Metronidazole + 125mg Diloxanide per 5ml)
- Frequency
- Three times daily
- Tracking Notes
- Always consult a pediatrician. Ensure child is well hydrated.
- Body Weight
- 8-10 kg
- Dose
- 2.5 ml of pediatric suspension (100mg Metronidazole + 125mg Diloxanide per 5ml)
- Frequency
- Three times daily
- Tracking Notes
- Administer with food to reduce gastrointestinal side effects.
- Body Weight
- 11-15 kg
- Dose
- 3.75 ml to 5 ml of pediatric suspension (100mg Metronidazole + 125mg Diloxanide per 5ml)
- Frequency
- Three times daily
- Tracking Notes
- Ensure the patient completes the standard 5 to 10 day course as prescribed.
- Body Weight
- 16-20 kg
- Dose
- 5 ml of pediatric suspension (100mg Metronidazole + 125mg Diloxanide per 5ml)
- Frequency
- Three times daily
- Tracking Notes
- Watch for side effects like metallic taste, nausea, or dark urine, which are temporary.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Not recommended / Not routine | Use only if explicitly prescribed by a pediatrician | Safety and efficacy in infants under 5 kg or below 6 months have not been fully established. |
| 5-7 kg | 1.25 ml to 2.5 ml of pediatric suspension (100mg Metronidazole + 125mg Diloxanide per 5ml) | Three times daily | Always consult a pediatrician. Ensure child is well hydrated. |
| 8-10 kg | 2.5 ml of pediatric suspension (100mg Metronidazole + 125mg Diloxanide per 5ml) | Three times daily | Administer with food to reduce gastrointestinal side effects. |
| 11-15 kg | 3.75 ml to 5 ml of pediatric suspension (100mg Metronidazole + 125mg Diloxanide per 5ml) | Three times daily | Ensure the patient completes the standard 5 to 10 day course as prescribed. |
| 16-20 kg | 5 ml of pediatric suspension (100mg Metronidazole + 125mg Diloxanide per 5ml) | Three times daily | Watch for side effects like metallic taste, nausea, or dark urine, which are temporary. |
Formulation
Purpose
Treatment of intestinal and extra-intestinal amoebiasis, amoebic dysentery, and mixed intestinal infections caused by susceptible protozoa and bacteria.
Generic Name
Metronidazole + Diloxanide FuroateScheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.