Dilox
Dilox contains Diloxanide Furoate, an effective luminal amebicide. It acts primarily in the bowel lumen to eliminate protozoa, specifically Entamoeba histolytica. It is commonly used as a primary treatment for asymptomatic cyst passers or as a sequential treatment following tissue amebicides like metronidazole to ensure complete eradication of the parasite.
Dosage by Body Weight
Standard adult dose is 500 mg taken orally three times daily for 10 days. Pediatric dosage is calculated at 20 mg/kg body weight per day, divided into three doses, for 10 days. It is recommended to take this medication after meals to minimize gastrointestinal discomfort.
- Body Weight
- Below 5 kg
- Dose
- Not routine
- Frequency
- Use only if prescribed
- Tracking Notes
- Safety and efficacy in infants under 5 kg (or under 2 years of age) have not been fully established.
- Body Weight
- 5-7 kg
- Dose
- 33 mg to 46 mg
- Frequency
- Three times daily for 10 days
- Tracking Notes
- Requires pediatric suspension or precise compounding of tablets. Use under strict medical supervision.
- Body Weight
- 8-10 kg
- Dose
- 53 mg to 66 mg
- Frequency
- Three times daily for 10 days
- Tracking Notes
- Ensure exact dosing. Do not exceed 200 mg total daily intake for this weight range.
- Body Weight
- 11-15 kg
- Dose
- 73 mg to 100 mg
- Frequency
- Three times daily for 10 days
- Tracking Notes
- Monitor for common side effects such as flatulence, nausea, or vomiting.
- Body Weight
- 16-20 kg
- Dose
- 106 mg to 133 mg
- Frequency
- Three times daily for 10 days
- Tracking Notes
- Complete the full 10-day course to prevent relapse of the amoebic infection.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Not routine | Use only if prescribed | Safety and efficacy in infants under 5 kg (or under 2 years of age) have not been fully established. |
| 5-7 kg | 33 mg to 46 mg | Three times daily for 10 days | Requires pediatric suspension or precise compounding of tablets. Use under strict medical supervision. |
| 8-10 kg | 53 mg to 66 mg | Three times daily for 10 days | Ensure exact dosing. Do not exceed 200 mg total daily intake for this weight range. |
| 11-15 kg | 73 mg to 100 mg | Three times daily for 10 days | Monitor for common side effects such as flatulence, nausea, or vomiting. |
| 16-20 kg | 106 mg to 133 mg | Three times daily for 10 days | Complete the full 10-day course to prevent relapse of the amoebic infection. |
Formulation
Purpose
Treatment of asymptomatic and chronic intestinal amoebiasis (luminal amoebiasis) caused by Entamoeba histolytica.
Generic Name
Diloxanide furoateScheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.