Desipramine
A tricyclic antidepressant (TCA) that acts primarily as a norepinephrine reuptake inhibitor. Use has declined in favor of newer ADHD drugs.
Dosage by Body Weight
Pediatric dose: 1-3 mg/kg/day. **Requires baseline and follow-up ECGs** to monitor for cardiac arrhythmias.
- Body Weight
- Over 30 kg
- Dose
- 25 mg to 50 mg
- Frequency
- Once daily or divided
- Tracking Notes
- High risk in overdose; keep securely stored.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Over 30 kg | 25 mg to 50 mg | Once daily or divided | High risk in overdose; keep securely stored. |
Formulation
Tablet
Purpose
Treatment of ADHD (off-label) and nocturnal enuresis in older children and adolescents.
Generic Name
Desipramine Hydrochloride
Branded Drug Names
Desipramine is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:
- Norpramin
Scheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.
Alternatives
ImipramineAtomoxetine