Cyklokapron
Cyklokapron (tranexamic acid) is an antifibrinolytic medication. It works by blocking the breakdown of blood clots, thereby helping to control and reduce excessive bleeding. It is commonly used both pre- and post-operatively, especially in cardiac, orthopedic, and gynecological surgeries, as well as for treating acute bleeding episodes.
Dosage by Body Weight
Dosage depends on the clinical indication and patient weight. For dental extraction in hemophilia, the typical adult oral dose is 25 mg/kg 3 to 4 times daily, starting one day prior to the procedure. For heavy menstrual bleeding, standard dosing is 1300 mg orally three times daily for up to 5 days during menstruation. Adjustments are required for patients with renal impairment.
- Body Weight
- Below 5 kg
- Dose
- Not routine
- Frequency
- Use only if prescribed
- Tracking Notes
- Safety and efficacy in infants are not fully established. Use only under strict specialist supervision.
- Body Weight
- 5-7 kg
- Dose
- 100 mg - 140 mg
- Frequency
- 3 to 4 times daily
- Tracking Notes
- Based on a standard pediatric oral dose of approximately 20 mg/kg. May require specialized liquid compounding.
- Body Weight
- 8-10 kg
- Dose
- 160 mg - 200 mg
- Frequency
- 3 to 4 times daily
- Tracking Notes
- Based on a standard pediatric oral dose of approximately 20 mg/kg.
- Body Weight
- 11-15 kg
- Dose
- 220 mg - 300 mg
- Frequency
- 3 to 4 times daily
- Tracking Notes
- Based on a standard pediatric oral dose of approximately 20 mg/kg.
- Body Weight
- 16-20 kg
- Dose
- 320 mg - 400 mg
- Frequency
- 3 to 4 times daily
- Tracking Notes
- Based on a standard pediatric oral dose of approximately 20 mg/kg.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Not routine | Use only if prescribed | Safety and efficacy in infants are not fully established. Use only under strict specialist supervision. |
| 5-7 kg | 100 mg - 140 mg | 3 to 4 times daily | Based on a standard pediatric oral dose of approximately 20 mg/kg. May require specialized liquid compounding. |
| 8-10 kg | 160 mg - 200 mg | 3 to 4 times daily | Based on a standard pediatric oral dose of approximately 20 mg/kg. |
| 11-15 kg | 220 mg - 300 mg | 3 to 4 times daily | Based on a standard pediatric oral dose of approximately 20 mg/kg. |
| 16-20 kg | 320 mg - 400 mg | 3 to 4 times daily | Based on a standard pediatric oral dose of approximately 20 mg/kg. |
Formulation
Purpose
To prevent or reduce excessive bleeding in various conditions such as heavy menstrual bleeding, severe nosebleeds, major trauma, and dental procedures in patients with hemophilia.
Generic Name
Tranexamic acidScheduled Drug
No. This medicine is generally not treated as a scheduled/prescription-only drug in common consumer references, but local rules may vary.