Cisplatin
Cisplatin is a platinum-based chemotherapy drug used to treat various types of cancers. It works by binding to DNA and interfering with cell replication, which leads to cancer cell death. It is a highly potent medication that requires intravenous administration and intensive clinical monitoring.
Dosage by Body Weight
Cisplatin dosage is highly individualized. It is calculated based on the patient's Body Surface Area (BSA in mg/m²) rather than body weight alone. Administered only by qualified healthcare professionals in a clinical setting.
- Body Weight
- Below 5 kg
- Dose
- BSA-based calculation only
- Frequency
- Per oncology protocol
- Tracking Notes
- Highly specialized pediatric oncology dosing required. Extreme risk of ototoxicity and nephrotoxicity.
- Body Weight
- 5-7 kg
- Dose
- BSA-based calculation only
- Frequency
- Per oncology protocol
- Tracking Notes
- Requires intensive pre- and post-treatment hydration to prevent renal damage.
- Body Weight
- 8-10 kg
- Dose
- BSA-based calculation only
- Frequency
- Per oncology protocol
- Tracking Notes
- Frequent monitoring of renal function, electrolytes, and audiology is mandatory.
- Body Weight
- 11-15 kg
- Dose
- BSA-based calculation only
- Frequency
- Per oncology protocol
- Tracking Notes
- Usually administered alongside vigorous antiemetic therapy to control nausea.
- Body Weight
- 16-20 kg
- Dose
- BSA-based calculation only
- Frequency
- Per oncology protocol
- Tracking Notes
- Dosing must be strictly computed using Body Surface Area formulas.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | BSA-based calculation only | Per oncology protocol | Highly specialized pediatric oncology dosing required. Extreme risk of ototoxicity and nephrotoxicity. |
| 5-7 kg | BSA-based calculation only | Per oncology protocol | Requires intensive pre- and post-treatment hydration to prevent renal damage. |
| 8-10 kg | BSA-based calculation only | Per oncology protocol | Frequent monitoring of renal function, electrolytes, and audiology is mandatory. |
| 11-15 kg | BSA-based calculation only | Per oncology protocol | Usually administered alongside vigorous antiemetic therapy to control nausea. |
| 16-20 kg | BSA-based calculation only | Per oncology protocol | Dosing must be strictly computed using Body Surface Area formulas. |
Formulation
Purpose
Treatment of advanced or metastatic cancers, primarily testicular, ovarian, and bladder cancers, as well as head, neck, and lung cancers.
Generic Name
CisplatinBranded Drug Names
Cisplatin is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:
Scheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.