Bio Statin
Bio Statin contains the active ingredient nystatin, an antifungal polyene antibiotic. It is used to treat fungal infections of the gastrointestinal tract and oral cavity. Nystatin works by binding to sterols in the fungal cell membrane, causing cell leakage and death. It is poorly absorbed from the gastrointestinal tract, meaning its action is primarily local.
Dosage by Body Weight
For oral thrush, the suspension should be held in the mouth or swished around for as long as possible before swallowing. For intestinal candidiasis, capsules or suspension are swallowed directly. Dosage is determined by a healthcare provider based on age and clinical response rather than weight alone.
- Body Weight
- Below 5 kg
- Dose
- 100,000 units (1 mL suspension)
- Frequency
- 4 times daily
- Tracking Notes
- Administer after feeding. Use dropper to place half of the dose in each side of the mouth. Avoid feeding for 5-10 minutes after.
- Body Weight
- 5-7 kg
- Dose
- 100,000 to 200,000 units (1-2 mL suspension)
- Frequency
- 4 times daily
- Tracking Notes
- Divide dose between both sides of the mouth. Continue use for at least 48 hours after symptoms disappear.
- Body Weight
- 8-10 kg
- Dose
- 200,000 units (2 mL suspension)
- Frequency
- 4 times daily
- Tracking Notes
- Coat the inside of the mouth. Do not mix with food or milk as it reduces efficacy.
- Body Weight
- 11-15 kg
- Dose
- 200,000 to 500,000 units (2-5 mL suspension)
- Frequency
- 4 times daily
- Tracking Notes
- Swish and retain in the mouth as long as possible before swallowing.
- Body Weight
- 16-20 kg
- Dose
- 500,000 units (5 mL suspension or 1 capsule)
- Frequency
- 3 to 4 times daily
- Tracking Notes
- Capsules may be used if the child can safely swallow them. Otherwise, use the oral suspension.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | 100,000 units (1 mL suspension) | 4 times daily | Administer after feeding. Use dropper to place half of the dose in each side of the mouth. Avoid feeding for 5-10 minutes after. |
| 5-7 kg | 100,000 to 200,000 units (1-2 mL suspension) | 4 times daily | Divide dose between both sides of the mouth. Continue use for at least 48 hours after symptoms disappear. |
| 8-10 kg | 200,000 units (2 mL suspension) | 4 times daily | Coat the inside of the mouth. Do not mix with food or milk as it reduces efficacy. |
| 11-15 kg | 200,000 to 500,000 units (2-5 mL suspension) | 4 times daily | Swish and retain in the mouth as long as possible before swallowing. |
| 16-20 kg | 500,000 units (5 mL suspension or 1 capsule) | 3 to 4 times daily | Capsules may be used if the child can safely swallow them. Otherwise, use the oral suspension. |
Formulation
Purpose
Treatment of intestinal candidiasis (moniliasis) and prevention of oral thrush (Candida infections)
Generic Name
NystatinScheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.