Amoxicillin and Clavulanate

The clavulanate component prevents bacteria from destroying the amoxicillin, broadening the spectrum of bacteria it can kill.

Dosage by Body Weight

Dosed based on the amoxicillin component (25-45 mg/kg/day for standard, up to 90 mg/kg/day for high-dose).

  1. Body Weight
    5-9 kg
    Dose
    125 mg to 200 mg (Amoxicillin portion)
    Frequency
    Twice daily
    Tracking Notes
    Refrigerate suspension and discard after 7-10 days.
  2. Body Weight
    10-15 kg
    Dose
    200 mg to 400 mg (Amoxicillin portion)
    Frequency
    Twice daily
    Tracking Notes
    Take at the start of a meal to reduce GI upset.

Formulation

TabletSuspension

Purpose

Combination antibiotic used for infections resistant to amoxicillin alone, such as sinus or ear infections.

Generic Name

Co-amoxiclav

Branded Drug Names

Amoxicillin and Clavulanate is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:

Scheduled Drug

Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.

Alternatives

Safety Advice

Alcohol

CAUTION

Amoxicillin and Clavulanate: Alcohol may worsen infection-related dehydration, dizziness, or stomach upset. Avoid or limit alcohol during antibiotic treatment.

Pregnancy

SAFE IF PRESCRIBED

Amoxicillin and Clavulanate: Use during pregnancy only when prescribed for a bacterial infection; the prescriber will choose the safest suitable antibiotic.

Breast Feeding

SAFE IF PRESCRIBED

Amoxicillin and Clavulanate: Many antibiotics are compatible with breastfeeding when prescribed, but monitor the infant for diarrhea, rash, or thrush.

Driving

SAFE

Amoxicillin and Clavulanate: Usually does not affect driving, but dizziness, weakness, or illness symptoms can occur. Avoid driving if affected.

Liver

CAUTION

Amoxicillin and Clavulanate: Use caution in liver disease or if jaundice, dark urine, or severe fatigue occurs during treatment.

Kidney

CAUTION

Amoxicillin and Clavulanate: Some antibiotics require dose adjustment or monitoring in kidney disease. Use exactly as prescribed.

Disclaimer: This information is for educational purposes only. WHO references and weight bands are simplified for tracking and must not replace medical advice. Always consult with a healthcare professional before starting or changing any medication.