Amoxicillin and Clavulanate
The clavulanate component prevents bacteria from destroying the amoxicillin, broadening the spectrum of bacteria it can kill.
Dosage by Body Weight
Dosed based on the amoxicillin component (25-45 mg/kg/day for standard, up to 90 mg/kg/day for high-dose).
- Body Weight
- 5-9 kg
- Dose
- 125 mg to 200 mg (Amoxicillin portion)
- Frequency
- Twice daily
- Tracking Notes
- Refrigerate suspension and discard after 7-10 days.
- Body Weight
- 10-15 kg
- Dose
- 200 mg to 400 mg (Amoxicillin portion)
- Frequency
- Twice daily
- Tracking Notes
- Take at the start of a meal to reduce GI upset.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| 5-9 kg | 125 mg to 200 mg (Amoxicillin portion) | Twice daily | Refrigerate suspension and discard after 7-10 days. |
| 10-15 kg | 200 mg to 400 mg (Amoxicillin portion) | Twice daily | Take at the start of a meal to reduce GI upset. |
Formulation
Purpose
Combination antibiotic used for infections resistant to amoxicillin alone, such as sinus or ear infections.
Generic Name
Co-amoxiclavBranded Drug Names
Amoxicillin and Clavulanate is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:
Scheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.
Alternatives
Safety Advice
Alcohol
CAUTIONAmoxicillin and Clavulanate: Alcohol may worsen infection-related dehydration, dizziness, or stomach upset. Avoid or limit alcohol during antibiotic treatment.
Pregnancy
SAFE IF PRESCRIBEDAmoxicillin and Clavulanate: Use during pregnancy only when prescribed for a bacterial infection; the prescriber will choose the safest suitable antibiotic.
Breast Feeding
SAFE IF PRESCRIBEDAmoxicillin and Clavulanate: Many antibiotics are compatible with breastfeeding when prescribed, but monitor the infant for diarrhea, rash, or thrush.
Driving
SAFEAmoxicillin and Clavulanate: Usually does not affect driving, but dizziness, weakness, or illness symptoms can occur. Avoid driving if affected.
Liver
CAUTIONAmoxicillin and Clavulanate: Use caution in liver disease or if jaundice, dark urine, or severe fatigue occurs during treatment.
Kidney
CAUTIONAmoxicillin and Clavulanate: Some antibiotics require dose adjustment or monitoring in kidney disease. Use exactly as prescribed.