Diphenhydramine
A sedating antihistamine that also has antitussive (cough suppressing) and anti-nausea properties.
Dosage by Body Weight
Not recommended for children under 2-6 years in many regions due to sedation. Pediatric dose: 1.25 mg/kg per dose.
- Body Weight
- 10-15 kg
- Dose
- 12.5 mg
- Frequency
- Every 4-6 hours
- Tracking Notes
- May cause significant drowsiness or paradoxical excitability.
- Body Weight
- 16-25 kg
- Dose
- 12.5 mg to 25 mg
- Frequency
- Every 4-6 hours
- Tracking Notes
- Max 150 mg per day for children.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| 10-15 kg | 12.5 mg | Every 4-6 hours | May cause significant drowsiness or paradoxical excitability. |
| 16-25 kg | 12.5 mg to 25 mg | Every 4-6 hours | Max 150 mg per day for children. |
Formulation
Purpose
First-generation antihistamine used for allergies, motion sickness, and as a sleep aid.
Generic Name
Diphenhydramine HydrochlorideBranded Drug Names
Diphenhydramine is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:
Scheduled Drug
No. This medicine is generally not treated as a scheduled/prescription-only drug in common consumer references, but local rules may vary.
Alternatives
Safety Advice
Alcohol
CAUTIONDiphenhydramine: Alcohol may increase dizziness, stomach upset, dehydration, or other side effects. Avoid or limit alcohol and follow medical advice.
Pregnancy
SAFE IF PRESCRIBEDDiphenhydramine: Use during pregnancy only if prescribed after a healthcare provider weighs the benefits and risks.
Breast Feeding
SAFE IF PRESCRIBEDDiphenhydramine: Use while breastfeeding only with healthcare provider guidance, especially for repeated or long-term treatment.
Driving
CAUTIONDiphenhydramine: This medicine may cause dizziness, drowsiness, weakness, or blurred vision in some people. Avoid driving if affected.
Liver
CAUTIONDiphenhydramine: Use with caution in liver disease and consult your healthcare provider if you have abnormal liver tests or jaundice.
Kidney
CAUTIONDiphenhydramine: Use with caution in kidney disease because dose adjustment or monitoring may be needed for some patients.